Recombinant Dog Plasminogen Activator, Urokinase

Species :	Dog
Source :	Insect Cells
Tag :	Non
Description :	This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer disease and also with decreased affinity for fibrin-binding. The protein encoded by this gene converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. This gene"s proprotein is cleaved at a Lys-Ile bond by plasmin to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain.
Form :	Frozen liquid.
Buffer :	0.05M Sodium Acetate; 0.1M NaCl; 1mM EDTA; pH 5.0.
Concentration :	4.0 mg/ml.
Aliquot :	1 x 0.1 mg.
Shipping Conditions :	Dry ice.
Storage :	Store at -70°C.

Gene Name	PLAU plasminogen activator, urokinase [ Canis lupus familiaris ]
Synonyms	PLAU; plasminogen activator, urokinase; plasminogen activator, urokinase; urokinase-type plasminogen activator
Gene ID	403426
mRNA Refseq	XM_536394
Protein Refseq	XP_536394
Chromosome Location	4
Pathway	Complement and coagulation cascades