Recombinant Drosophila melanogaster tau Protein (Full length)

• Cat.No.: tau-38D
• Product Overview: Recombinant full-length Drosophila melanogaster tag-free Tau-361 was expressed in E. coli cells.

Specification

• Description: Drosophila melanogaster Tau-361 and human Tau-441 are homologs with amino acid sequence similarities and share functional properties in microtubule binding and stability. Tau-361 exhibits 46% identity and 66% similarity with human Tau-441. Tau-361 contains five putative microtubule binding domain (MTBD) repeats, but does not contain the N-terminal MTBD repeats found in human Tau-441. Drosophila melanogaster is a widely used powerful model organism utilized to investigate in vivo toxicity of proteins linked to neurodegenerative diseases, particularly Alzheimer’s disease where the accumulation of post-translationally modified Tau species leads to the formation of intracellular neurofibrillary tangles and subsequent neuronal death.
• Source: E.coli
• Species: Drosophila melanogaster
• Molecular Mass: Observed MW: ~53 kDa.
  Calculated MW: ~41 kDa.
• Protein Length: Full Length
• Purity: The purity of Tau-361 was determined to be > 70 % by densitometry.
• Stability: One year at -70 centigrade from date of shipment.
• Storage: Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.2 μg/μL
• Storage Buffer: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0,25mM DTT, 25% glycerol.
• Shipping: Dry ice

Gene Information

• Gene Name: tau [ Drosophila melanogaster (fruit fly) ]
• Official Symbol: tau
• Synonyms: tau; Dmel_CG31057; Dmel_CG31058; Dmel_CG34294; BcDNA:RE16764; CG12881; CG31057; CG31058; CG34294; CG45110; CG5606; d-tau; Dmel\CG45110; dtau; dTau; dTAU; Tau; tau; CG45110-PA; CG45110-PB; CG45110-PC; CG45110-PE; CG45110-PF; CG45110-PG; CG45110-PH; CG45110-PI; CG45110-PJ; CG45110-PK; CG45110-PL; CG45110-PM; CG45110-PN; CG45110-PO; tau-PA; tau-PB; tau-PC; tau-PE; tau-PF; tau-PG; tau-PH; tau-PI; tau-PJ; tau-PK; tau-PL; tau-PM; tau-PN; tau-PO
• Gene ID: 326116
• mRNA Refseq: NM_143318
• Protein Refseq: NP_651575
• UniProt ID: Q9VB13