Recombinant E. coli LT-IIc, His-tagged
Cat.No. : | LT-912E |
Product Overview : | Type II heat-labile enterotoxin, LT-IIc, from Escherichia coli was produced recombinantly in E. coli and purified to homogeneity using a combination of nickel affinity and gel filtration chromatography. Protein has been His-tagged at the COOH ends of each of the five B subunits. |
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Description : | LT-IIc is a type II heat-labile enterotoxin produced by certain strains of Escherichia coli. LT-IIc binds to gangliosides GM1, GM2, GM3, and GD1a, but has no detectable binding activity for GD1b, GQ1b, and GT1b, three gangliosides which are avidly bound by LT-IIa, another type II heat-labile entertoxin. LT-IIc binds to GM1, a ganglioside also bound by cholera toxin, a type I heat-labile enterotoxin, and by LT-IIa, but not by LT-IIb, the third member of the type II heat-labile enterotoxin family. The molecule induces high levels of cAMP in the cell upon intoxication. The enterotoxin is also a very strong mucosal and systemic adjuvant when administered by intranasal or intradermal routes. |
Source : | E. coli |
Species : | E. coli |
Tag : | His |
Form : | Powder |
Molecular Mass : | 80.36kDa, (A subunit + five B subunits) |
Purity : | > 95% |
Storage : | Store at -20 centigrade (long term). Store at +4 centigrade when dissolved in aqueous solution (pH 7.0 to pH 7.4). |
Concentration : | 5mg/ml |
Storage Buffer : | Water (pH 7.0 to 7.4) |
Gene Name : | Heat-Labile Enterotoxin LT-Iic |
Official Symbol : | LT |
Synonyms : | Type II heat-labile enterotoxin; Heat-Labile Enterotoxin; LT toxin; LT-Iic |
Gene Name : | Heat-Labile Enterotoxin LT-Iic |
Official Symbol : | LT |
Synonyms : | Type II heat-labile enterotoxin; Heat-Labile Enterotoxin; LT toxin; LT-Iic |
Products Types
◆ Recombinant Protein | ||
LT-2764P | Recombinant Pan-species (General) LT Protein, His-tagged | +Inquiry |
LT-911E | Recombinant E. coli LT-IIb, His-tagged | +Inquiry |
LT-910E | Recombinant E. coli LT-IIa, His-tagged | +Inquiry |
LT-3345P | Recombinant Pan-species LT protein, His-GST-tagged | +Inquiry |
LT-3346P | Recombinant Pan-species LT protein, His-SUMO-tagged | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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