Recombinant Equine CCL11

• Cat.No.: CCL11-138E
• Product Overview: Recombinant Equine CCL11 protein was expressed in Yeast and purified by using Ion-exchange chromatography, 9.0 kDa (78 aa).

Specification

• Description: Chemokine ligand 11 (CCL11) belongs to the CC chemokine family and is commonly known as Eotaxin-1. There are at least 27 distinct members of the C-C subgroup reported for mammals. CC chemokines induce the migration of monocytes and other cell types such as NK cells and dendritic cells. CCL11 (Eotaxin-1) selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. Endothelial cells, smooth muscle cells, epithelial cells, alveolar macrophages and eosinophils are known to produce CCL11 (Eotaxin).
• Source: Yeast
• Species: Equine
• Form: Lyophilized without carrier protein.
• Molecular Mass: Equine CCL11 has a predicted molecular weight of 9.0 kDa.
• AA Sequence: AQPVSISTVC CFNVASRKIS FQRLQSYRKI TSSKCPQKAV IFKTKQAKKI CADPKQKWVQ DAMKYLDENS RTTKYSSF
• Purity: >95% as visualized by SDS-PAGE analysis.
• Applications: The Equine CCL11/Eotaxin-1 protein can be used in cell culture, as an CCL11 ELISA Standard, and as a Western Blot Control.
• Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
• Reconstitution: Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.

Gene Information

• Gene Name: CCL11 chemokine (C-C motif) ligand 11 [ Equus caballus ]
• Official Symbol: CCL11
• Synonyms: eotaxin; C-C motif chemokine 11; small-inducible cytokine A11
• Gene ID: 100033949
• mRNA Refseq: NM_001081871
• Protein Refseq: NP_001075340
• UniProt ID: Q9TTQ4
• Chromosome Location: chromosome: 11
• Pathway: Asthma, organism-specific biosystem; Asthma, conserved biosystem; Chemokine signaling pathway, organism-specific biosystem