Recombinant Full Legnth Human RHEB, His-tagged
Cat.No. : | RHEB-2289H |
Product Overview : | Recombinant Human RHEB protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
Availability | February 11, 2025 |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 1-184aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | RHEB Ras homolog enriched in brain [ Homo sapiens ] |
Official Symbol : | RHEB |
Synonyms : | RHEB; Ras homolog enriched in brain; Ras homolog enriched in brain 2 , RHEB2; GTP-binding protein Rheb; Ras homolog enriched in brain 2; RHEB2; MGC111559; |
Gene ID : | 6009 |
mRNA Refseq : | NM_005614 |
Protein Refseq : | NP_005605 |
MIM : | 601293 |
UniProt ID : | Q15382 |
Chromosome Location : | 7q36 |
Pathway : | Energy dependent regulation of mTOR by LKB1-AMPK, organism-specific biosystem; IRS-mediated signalling, organism-specific biosystem; IRS-related events, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; Insulin receptor signalli |
Function : | GTP binding; GTPase activity; metal ion binding; nucleotide binding; |
Products Types
◆ Recombinant Protein | ||
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RHEB-4691R | Recombinant Rat RHEB Protein, His (Fc)-Avi-tagged | +Inquiry |
RHEB-1181H | Recombinant Human RHEB Protein, MYC/DDK-tagged | +Inquiry |
Rheb-5504M | Recombinant Mouse Rheb Protein, Myc/DDK-tagged | +Inquiry |
RHEB-6179H | Recombinant Full Length Human RHEB Protein (Met1-Met184), N-GST tagged | +Inquiry |
◆ Lysates | ||
RHEB-001HCL | Recombinant Human RHEB cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewResearchers using RHEB protein can benefit from its high purity and quality, ensuring reliable results.
the RHEB protein is available in different formats, including recombinant and purified variants.
This flexibility allows researchers to select the most suitable form for their particular experimental setup, enhancing the efficiency and accuracy of their trials.
Q&As (5)
Ask a questionRHEB directly interacts with the mTOR pathway, a key regulator of cell growth. Understanding this interaction provides insights for developing drugs that target this pathway in diseases like cancer.
Some experimental drugs targeting RHEB are in preclinical development, showing promise in modulating cell growth and survival.
RHEB's involvement in cell growth makes it a potential target for cancer therapy. Understanding its role may lead to the development of targeted therapies.
Research is underway to evaluate the therapeutic potential of targeting RHEB in cancer treatment, with several clinical trials exploring its role as a therapeutic target.
Dysregulation of RHEB is associated with various diseases, including cancer and neurological disorders, due to its impact on cell growth and survival pathways.
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