Recombinant Full Length Human ABHD12 Protein, GST-tagged
Cat.No. : | ABHD12-828HF |
Product Overview : | Human ABHD12 full-length ORF ( NP_056415.1, 1 a.a. - 404 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 72 kDa |
Protein Length : | 404 amino acids |
AA Sequence : | MRKRTEPVAL EHERCAAAGS SSSGSAAAAL DADCRLKQNL RLTGPAAAEP RCAADAGMKR ALGRRKGVWL RLRKILFCVL GLYIAIPFLI KLCPGIQAKL IFLNFVRVPY FIDLKKPQDQ GLNHTCNYYL QPEEDVTIGV WHTVPAVWWK NAQGKDQMWY EDALASSHPI ILYLHGNAGT RGGDHRVELY KVLSSLGYHV VTFDYRGWGD SVGTPSERGM TYDALHVFDW IKARSGDNPV YIWGHSLGTG VATNLVRRLC ERETPPDALI LESPFTNIRE EAKSHPFSVI YRYFPGFDWF FLDPITSSGI KFANDENVKH ISCPLLILHA EDDPVVPFQL GRKLYSIAAP ARSFRDFKVQ FVPFHSDLGY RHKYIYKSPE LPRILRPQQG PGSSPDPSMW SELV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ABHD12 abhydrolase domain containing 12 [ Homo sapiens ] |
Official Symbol : | ABHD12 |
Synonyms : | ABHD12; abhydrolase domain containing 12; C20orf22, chromosome 20 open reading frame 22; monoacylglycerol lipase ABHD12; ABHD12A; BEM46L2; dJ965G21.2; DKFZP434P106; 2-arachidonoylglycerol hydrolase; abhydrolase domain-containing protein 12; PHARC; C20orf22; DKFZp434P106; |
Gene ID : | 26090 |
mRNA Refseq : | NM_001042472 |
Protein Refseq : | NP_001035937 |
MIM : | 613599 |
UniProt ID : | Q8N2K0 |
Products Types
◆ Recombinant Protein | ||
ABHD12-15R | Recombinant Rhesus Macaque ABHD12 Protein, His (Fc)-Avi-tagged | +Inquiry |
ABHD12-12C | Recombinant Cynomolgus Monkey ABHD12 Protein, His (Fc)-Avi-tagged | +Inquiry |
ABHD12-247H | Recombinant Human ABHD12 Protein, His (Fc)-Avi-tagged | +Inquiry |
ABHD12-73R | Recombinant Rat ABHD12 Protein, His (Fc)-Avi-tagged | +Inquiry |
ABHD12-212M | Recombinant Mouse ABHD12 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ABHD12-9HCL | Recombinant Human ABHD12 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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