Recombinant Full Length Human AKTIP Protein, GST-tagged

• Cat.No.: AKTIP-5125HF
• Product Overview: Human FTS full-length ORF ( AAH01134, 1 a.a. - 292 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKBs regulatory sites. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 57.86 kDa
• Protein Length: 292 amino acids
• AA Sequence: MNPFWSMSTSSVRKRSEGEEKTLTG DVKTSPPRTAPKKQLPSIPKNALPI TKPTSPAPAAQSTNGTHASYGPFYL EYSLLAEFTLVVKQKLPGVYVQPSY RSALMWFGVIFIRHGLYQDGVFKFT VYIPDNYPDGDCPRLVFDIPVFHPL VDPTSGELDVKRAFAKWRRNHNHIW QVLMYARRVFYKIDTASPLNPEAAV LYEKDIQLFKSKVVDSVKVCTARLF DQPKIEDPYAISFSPWNPSVHDEAR EKMLTQKKPEEQHNKSVHVAGLSWV KPGSVQPFSKEEKTVAT
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AKTIP AKT interacting protein [ Homo sapiens ]
• Official Symbol: AKTIP
• Synonyms: AKTIP; AKT interacting protein; FTS, fused toes (mouse) homolog, fused toes homolog (mouse); AKT-interacting protein; FLJ13258; fused toes homolog; fused toes protein homolog; FT1; FTS
• Gene ID: 64400
• mRNA Refseq: NM_001012398
• Protein Refseq: NP_001012398
• MIM: 608483
• UniProt ID: Q9H8T0