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Recombinant Full Length Human AP3M1 Protein, GST-tagged

Cat.No. : AP3M1-1221HF
Product Overview : Human AP3M1 full-length ORF ( NP_036227.1, 1 a.a. - 418 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 73.3 kDa
Protein Length : 418 amino acids
AA Sequence : MIHSLFLINC SGDIFLEKHW KSVVSQSVCD YFFEAQEKAA DVENVPPVIS TPHHYLISIY RDKLFFVSVI QTEVPPLFVI EFLHRVADTF QDYFGECSEA AIKDNVVIVY ELLEEMLDNG FPLATESNIL KELIKPPTIL RSVVNSITGS SNVGDTLPTG QLSNIPWRRA GVKYTNNEAY FDVVEEIDAI IDKSGSTVFA EIQGVIDACI KLSGMPDLSL SFMNPRLLDD VSFHPCIRFK RWESERVLSF IPPDGNFRLI SYRVSSQNLV AIPVYVKHSI SFKENSSCGR FDITIGPKQN MGKTIEGITV TVHMPKVVLN MNLTPTQGSY TFDPVTKVLT WDVGKITPQK LPSLKGLVNL QSGAPKPEEN PSLNIQFKIQ QLAISGLKVN RLDMYGEKYK PFKGVKYVTK AGKFQVRT
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : AP3M1 adaptor-related protein complex 3, mu 1 subunit [ Homo sapiens ]
Official Symbol : AP3M1
Synonyms : AP3M1; adaptor-related protein complex 3, mu 1 subunit; AP-3 complex subunit mu-1; mu3A-adaptin; mu-adaptin 3A; AP-3 adapter complex mu3A subunit; clathrin adaptor complex AP3, mu-3A subunit; adapter-related protein complex 3 mu-1 subunit; MGC22164
Gene ID : 26985
mRNA Refseq : NM_012095
Protein Refseq : NP_036227
MIM : 610366
UniProt ID : Q9Y2T2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (20)

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Is the therapeutic effect of recombinant AP3M1 dose-dependent? 11/15/2022

According to the current study, the therapeutic effect of AP3M1 may be dose-dependent, but the specific dose-effect needs to be further studied.

What is special about AP3M1 compared with other s? 10/12/2022

What makes AP3M1 special compared to other s may include its specific biological function and clinical application potential.

How long will it take for the study of AP3M1 to bear fruit? 09/29/2022

The study of AP3M1 is a long and complex process, and the specific time depends on several factors, including research progress and clinical trial progress.

What is the production cost of AP3M1 ? 08/26/2022

The production cost of AP3M1 may be affected by many factors, including production technology, purification method, etc.

Can recombinant AP3M1 be used in cancer treatment? 07/24/2022

The potential of recombinant AP3M1 in cancer therapy is being studied, but it has not yet been determined whether it can be used as an effective means of cancer treatment.

What is the potential of AP3M1 in drug delivery systems? 04/30/2022

The AP3M1 may have potential in drug delivery systems, but the specific applicability and advantages need to be further studied.

What is the research status of AP3M1 ? 02/04/2022

The research status of AP3M1 is a frontier subject, which is currently undergoing basic research and clinical trials.

Is recombinant AP3M1 involved in immune system regulation? 01/24/2022

Recombinant protein AP3M1 may be involved in immune system regulation, but the specific mechanism needs to be further studied.

Can AP3M1 be administered orally? 01/03/2022

Oral administration of AP3M1 may have certain challenges and limitations, and the specific applicability needs to be further studied.

What are the potential clinical applications of AP3M1 ? 12/08/2021

Potential clinical applications of recombinant AP3M1 may include the treatment of certain genetic diseases, cancer immunotherapy, etc.

How does the AP3M1 interact with the patient's immune system? 10/04/2020

The recombinant AP3M1 protein may interact with the patient's immune system, but the specific mechanism needs to be further studied.

Can recombinant AP3M1 be used to treat autoimmune diseases? 10/04/2020

Potential applications of recombinant AP3M1 include the treatment of autoimmune diseases, but the specific effects need to be further studied.

Is there any side effect of AP3M1 treatment? 08/31/2020

It is not known whether there are side effects of recombinant AP3M1 therapy, and further research and clinical trials are needed to determine its safety and side effects.

Does the lack of AP3M1 cause the occurrence of certain diseases? 08/08/2020

It has not yet been determined whether the deficiency of AP3M1 contributes to the development of certain diseases, and further research is needed.

Are there any drugs already on the market that contain AP3M1 ? 07/04/2020

At present, it is not known whether the drugs already on the market contain AP3M1 , and further inquiries may be required.

What is the biosynthesis mode of AP3M1 ? 02/21/2020

The biosynthesis of AP3M1 may include genetic engineering techniques, expressed and purified by transgenic cells or bioreactors.

Is the application of AP3M1 protected by intellectual property rights? 09/12/2019

The application of AP3M1 is protected by intellectual property rights, which needs to be verified, but generally involves new drug applications with some protection.

How to evaluate the biological activity of AP3M1 ? 07/16/2019

Evaluation of the biological activity of AP3M1 may include in vitro and animal model experiments.

What is the safety and efficacy of AP3M1 in clinical trials? 01/29/2019

At present, data on the safety and efficacy of recombinant AP3M1 in clinical trials have not been made public, and clinical trials are still required to determine it.

Which diseases can AP3M1 be used for diagnosis? 01/14/2019

The AP3M1 may be used in the diagnosis of some diseases, but the specific scope of application needs further research.

Customer Reviews (3)

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Reviews
12/28/2022

    I appreciate the quality of AP3M1 manufacturer, and their product repeatability is very good, which makes me more confident in the experimental results.

    11/27/2021

      The stability of AP3M1 is so good that it can be performed experimentally for a long time without affecting its performance and results.

      01/29/2019

        After using AP3M1, the repeatability of Western blot was significantly improved.

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