Recombinant Full Length Human AP3M1 Protein, GST-tagged
Cat.No. : | AP3M1-1221HF |
Product Overview : | Human AP3M1 full-length ORF ( NP_036227.1, 1 a.a. - 418 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 73.3 kDa |
Protein Length : | 418 amino acids |
AA Sequence : | MIHSLFLINC SGDIFLEKHW KSVVSQSVCD YFFEAQEKAA DVENVPPVIS TPHHYLISIY RDKLFFVSVI QTEVPPLFVI EFLHRVADTF QDYFGECSEA AIKDNVVIVY ELLEEMLDNG FPLATESNIL KELIKPPTIL RSVVNSITGS SNVGDTLPTG QLSNIPWRRA GVKYTNNEAY FDVVEEIDAI IDKSGSTVFA EIQGVIDACI KLSGMPDLSL SFMNPRLLDD VSFHPCIRFK RWESERVLSF IPPDGNFRLI SYRVSSQNLV AIPVYVKHSI SFKENSSCGR FDITIGPKQN MGKTIEGITV TVHMPKVVLN MNLTPTQGSY TFDPVTKVLT WDVGKITPQK LPSLKGLVNL QSGAPKPEEN PSLNIQFKIQ QLAISGLKVN RLDMYGEKYK PFKGVKYVTK AGKFQVRT |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | AP3M1 adaptor-related protein complex 3, mu 1 subunit [ Homo sapiens ] |
Official Symbol : | AP3M1 |
Synonyms : | AP3M1; adaptor-related protein complex 3, mu 1 subunit; AP-3 complex subunit mu-1; mu3A-adaptin; mu-adaptin 3A; AP-3 adapter complex mu3A subunit; clathrin adaptor complex AP3, mu-3A subunit; adapter-related protein complex 3 mu-1 subunit; MGC22164 |
Gene ID : | 26985 |
mRNA Refseq : | NM_012095 |
Protein Refseq : | NP_036227 |
MIM : | 610366 |
UniProt ID : | Q9Y2T2 |
Products Types
◆ Recombinant Protein | ||
AP3M1-190H | Recombinant Human AP3M1 Protein, His-tagged | +Inquiry |
AP3M1-606M | Recombinant Mouse AP3M1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ap3m1-3541R | Recombinant Rat Ap3m1, His-tagged | +Inquiry |
AP3M1-657H | Recombinant Human AP3M1 protein, GST-tagged | +Inquiry |
AP3M1-2889C | Recombinant Chicken AP3M1 | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (20)
Ask a questionAccording to the current study, the therapeutic effect of AP3M1 may be dose-dependent, but the specific dose-effect needs to be further studied.
What makes AP3M1 special compared to other s may include its specific biological function and clinical application potential.
The study of AP3M1 is a long and complex process, and the specific time depends on several factors, including research progress and clinical trial progress.
The production cost of AP3M1 may be affected by many factors, including production technology, purification method, etc.
The potential of recombinant AP3M1 in cancer therapy is being studied, but it has not yet been determined whether it can be used as an effective means of cancer treatment.
The AP3M1 may have potential in drug delivery systems, but the specific applicability and advantages need to be further studied.
The research status of AP3M1 is a frontier subject, which is currently undergoing basic research and clinical trials.
Recombinant protein AP3M1 may be involved in immune system regulation, but the specific mechanism needs to be further studied.
Oral administration of AP3M1 may have certain challenges and limitations, and the specific applicability needs to be further studied.
Potential clinical applications of recombinant AP3M1 may include the treatment of certain genetic diseases, cancer immunotherapy, etc.
The recombinant AP3M1 protein may interact with the patient's immune system, but the specific mechanism needs to be further studied.
Potential applications of recombinant AP3M1 include the treatment of autoimmune diseases, but the specific effects need to be further studied.
It is not known whether there are side effects of recombinant AP3M1 therapy, and further research and clinical trials are needed to determine its safety and side effects.
It has not yet been determined whether the deficiency of AP3M1 contributes to the development of certain diseases, and further research is needed.
At present, it is not known whether the drugs already on the market contain AP3M1 , and further inquiries may be required.
The biosynthesis of AP3M1 may include genetic engineering techniques, expressed and purified by transgenic cells or bioreactors.
The application of AP3M1 is protected by intellectual property rights, which needs to be verified, but generally involves new drug applications with some protection.
Evaluation of the biological activity of AP3M1 may include in vitro and animal model experiments.
At present, data on the safety and efficacy of recombinant AP3M1 in clinical trials have not been made public, and clinical trials are still required to determine it.
The AP3M1 may be used in the diagnosis of some diseases, but the specific scope of application needs further research.
Customer Reviews (3)
Write a reviewI appreciate the quality of AP3M1 manufacturer, and their product repeatability is very good, which makes me more confident in the experimental results.
The stability of AP3M1 is so good that it can be performed experimentally for a long time without affecting its performance and results.
After using AP3M1, the repeatability of Western blot was significantly improved.
Ask a Question for All AP3M1 Products
Required fields are marked with *
My Review for All AP3M1 Products
Required fields are marked with *
Inquiry Basket