|Product Overview :
||Human AP3M1 full-length ORF ( NP_036227.1, 1 a.a. - 418 a.a.) recombinant protein with GST-tag at N-terminal.
||The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016]
|Molecular Mass :
|AA Sequence :
||Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
||Best use within three months from the date of receipt of this protein.
||Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
|Storage Buffer :
||50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
12.5% SDS-PAGE Stained with Coomassie Blue.