Recombinant Full Length Human ARHGEF5 Protein, GST-tagged

• Cat.No.: ARHGEF5-1063HF
• Product Overview: Human ARHGEF5 full-length ORF ( AAH14555, 1 a.a. - 519 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 82.83 kDa
• Protein Length: 519 amino acids
• AA Sequence: MGGFSRRCSK LINSSQLLYQ EYSDVVLNKE IQSQQRLESL SETPGPSSPR QPRKALVSSE SYLQRLSMAS SGSLWQEIPV VRNSTVLLSM THEDQKLQEV KFELIVSEAS YLRSLNIAVD HFQLSTSLRA TLSNQEHQWL FSRLQDVRDV SATFLSDLEE NFENNIFSFQ VCDVVLNHAP DFRRVYLPYV TNQTYQERTF QSLMNSNSNF REVLEKLESD PVCQRLSLKS FLILPFQRIT RLKLLLQNIL KRTQPGSSEE AEATKAHHAL EQLIRDCNNN VQSMRRTEEL IYLSQKIEFE CKIFPLISQS RWLVKSGELT ALEFSASPGL RRKLNTRPVH LHLFNDCLLL SRPREGSRFL VFDHAPFSSI RGEKCEMKLH GPHKNLFRLF LRQNTQGAQA EFLFRTETQS EKLRWISALA MPREELDLLE CYNSPQVQCL RAYKPRENDE LALEKADVVM VTQQSSDGWL EGVRLSDGER GWFPVQQVEF ISNPEVRAQN LKEAHRVKTA KLQLVEQQA
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ARHGEF5 Rho guanine nucleotide exchange factor 5 [ Homo sapiens (human) ]
• Official Symbol: ARHGEF5
• Synonyms: ARHGEF5; Rho guanine nucleotide exchange factor 5; P60; TIM; GEF5; TIM1; rho guanine nucleotide exchange factor 5; Rho guanine nucleotide exchange factor (GEF) 5; ephexin-3; guanine nucleotide regulatory protein TIM; oncogene TIM; p60 TIM; transforming immortalized mammary oncogene
• Gene ID: 7984
• mRNA Refseq: NM_005435
• Protein Refseq: NP_005426
• MIM: 600888
• UniProt ID: Q12774