Recombinant Full Length Human ASPSCR1 Protein, GST-tagged

• Cat.No.: ASPSCR1-1298HF
• Product Overview: Human ASPSCR1 full-length ORF ( AAH18722, 1 a.a. - 553 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 86.57 kDa
• Protein Length: 553 amino acids
• AA Sequence: MAAPAGGGGS AVSVLAPNGR RHTVKVTPST VLLQVLEDTC RRQDFNPCEY DLKFQRSVLD LSLQWRFANL PNNAKLEMVP ASRSREGPEN MVRIALQLDD GSRLQDSFCS GQTLWELLSH FPQIRECLQH PGGATPVCVY TRDEVTGEAA LRGTTLQSLG LTGGSATIRF VMKCYDPVGK TPGSLGSSAS AGQAAASAPL PLESGELSRG DLSRPEDADT SGPCCEHTQE KQSTRAPAAA PFVPFSGGGQ RQGGPPGPTR PLTSSSAKLP KSLSSPGGPS KPKKSKSGQD PQQEQEQERE RDPQQEQERE RPVDREPVDR EPVVCHPDLE ERLQAWPAEL PDEFFELTVD DVRRRLAQLK SERKRLEEAP LVTKAFREAQ IKEKLERYPK VALRVLFPDR YVLQGFFRPS ETVGDLRDFV RSHLGNPELS FYLFITPPKT VLDDHTQTLF QANLFPAALV HLGAEEPAGV YLEPGLLEHA ISPSAADVLV ARYMSRAAGS PSPLPAPDPA PKSEPAAEEG ALVPPEPIPG TAQPVKRSLG KVPKWLKLPA SKR
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 [ Homo sapiens ]
• Official Symbol: ASPSCR1
• Synonyms: ASPSCR1; alveolar soft part sarcoma chromosome region, candidate 1; tether containing UBX domain for GLUT4; ASPL; ASPS; UBX domain protein 9; UBXD9; UBXN9; UBX domain-containing protein 9; alveolar soft part sarcoma locus; renal cell carcinoma, papillary, 17; renal papillary cell carcinoma protein 17; renal cell carcinoma gene on chromosome 17; alveolar soft part sarcoma chromosomal region candidate gene 1 protein; TUG; RCC17; ASPCR1; FLJ45380
• Gene ID: 79058
• mRNA Refseq: NM_001251888
• Protein Refseq: NP_001238817
• MIM: 606236
• UniProt ID: Q9BZE9