Recombinant Full Length Human ATF4 Protein, N-His-tagged
| Cat.No. : | ATF4-217HFL |
| Product Overview : | Recombinant Full Length Human ATF4 Protein, fused to His-tag at N-terminus, was expressed in E. coli. |
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| Species : | Human |
| Source : | E.coli |
| Tag : | His |
| Description : | This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. |
| Form : | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl. |
| Molecular Mass : | 38.4 kDa |
| AA Sequence : | A DNA sequence encoding human full-length ATF4. |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
| Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : | Store at -80 centigrade. |
| Concentration : | >50 ug/mL as determined by microplate BCA method. |
| Protein Families : | Transcription Factors |
| Protein Pathways : | GnRH signaling pathway, Long-term potentiation, MAPK signaling pathway, Neurotrophin signaling pathway, Prostate cancer |
| Full Length : | Full L. |
| Gene Name | ATF4 activating transcription factor 4 [ Homo sapiens (human) ] |
| Official Symbol | ATF4 |
| Synonyms | CREB2; TXREB; CREB-2; TAXREB67 |
| Gene ID | 468 |
| mRNA Refseq | NM_001675.4 |
| Protein Refseq | NP_001666.2 |
| MIM | 604064 |
| UniProt ID | P18848 |
Not For Human Consumption!
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