Recombinant Full Length Human B4GALT3 Protein, GST-tagged

• Cat.No.: B4GALT3-1655HF
• Product Overview: Human B4GALT3 full-length ORF ( NP_003770.1, 1 a.a. - 393 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 70.3 kDa
• Protein length: 393 amino acids
• AA Sequence: MLRRLLERPC TLALLVGSQL AVMMYLSLGG FRSLSALFGR DQGPTFDYSH PRDVYSNLSH LPGAPGGPPA PQGLPYCPER SPLLVGPVSV SFSPVPSLAE IVERNPRVEP GGRYRPAGCE PRSRTAIIVP HRAREHHLRL LLYHLHPFLQ RQQLAYGIYV IHQAGNGTFN RAKLLNVGVR EALRDEEWDC LFLHDVDLLP ENDHNLYVCD PRGPRHVAVA MNKFGYSLPY PQYFGGVSAL TPDQYLKMNG FPNEYWGWGG EDDDIATRVR LAGMKISRPP TSVGHYKMVK HRGDKGNEEN PHRFDLLVRT QNSWTQDGMN SLTYQLLARE LGPLYTNITA DIGTDPRGPR APSGPRYPPG SSQAFRQEML QRRPPARPGP LSTANHTALR GSH
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 [ Homo sapiens ]
• Official Symbol: B4GALT3
• Synonyms: B4GALT3; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3; beta-1,4-galactosyltransferase 3; beta4Gal T3; b4Gal-T3; beta-1,4-GalTase 3; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 3; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3; beta4Gal-T3
• Gene ID: 8703
• mRNA Refseq: NM_001199873
• Protein Refseq: NP_001186802
• MIM: 604014
• UniProt ID: O60512