Recombinant Full Length Human BAIAP2 Protein transcript variant 1, C-Myc/DDK-tagged
Cat.No. : | BAIAP2-12HFL |
Product Overview : | Recombinant Full Length Human BAIAP2 Protein transcript variant 1, fused to Myc/DDK-tag at C-terminus, was expressed in HEK293T. |
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Description : | The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Source : | HEK293T |
Species : | Human |
Tag : | Myc/DDK |
Form : | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol. |
Molecular Mass : | 57.2 kDa |
AA Sequence : | MSLSRSEEMHRLTENVYKTIMEQFN PSLRNFIAMGKNYEKALAGVTYAAK GYFDALVKMGELASESQGSK ELGDVLFQMAEVHRQIQNQLEEMLK SFHNELLTQLEQKVELDSRYLSAAL KKYQTEQRSKGDALDKCQAE LKKLRKKSQGSKNPQKYSDKELQYI DAISNKQGELENYVSDGYKTALTEE RRRFCFLVEKQCAVAKNSAA YHSKGKELLAQKLPLWQQACADPSK IPERAVQLMQQVASNGATLPSALSA SKSNLVISDPIPGAKPLPVP PELAPFVGRMSAQESTPIMNGVTGP DGEDYSPWADRKAAQPKSLSPPQSQ SKLSDSYSNTLPVRKSVTPK NSYATTAENKTLPRSSSMAAGLERN GRMRVKAIFSHAAGDNSTLLSFKEG DLITLLVPEARDGWHYGESE KTKMRGWFPFSYTRVLDSDGSDRLH MSLQQGKSSSTGNLLDKDDLAIPPP DYGAASRAFPAQTASGFKQR PYSVAVPAFSQGLDDYGARSMSSGS GTLVSTV TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Notes : | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >0.05 µg/µL as determined by microplate BCA method |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Adherens junction, Regulation of actin cytoskeleton |
Gene Name : | BAIAP2 BAR/IMD domain containing adaptor protein 2 [ Homo sapiens (human) ] |
Official Symbol : | BAIAP2 |
Synonyms : | BAP2; WAML; FLAF3; IRSP53 |
Gene ID : | 10458 |
mRNA Refseq : | NM_017450.3 |
Protein Refseq : | NP_059344.1 |
MIM : | 605475 |
UniProt ID : | Q9UQB8 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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