Recombinant Full Length Human BCAT1 Protein, GST-tagged

• Cat.No.: BCAT1-1608HF
• Product Overview: Human BCAT1 full-length ORF ( AAH33864, 1 a.a. - 320 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 60.94 kDa
• Protein Length: 320 amino acids
• AA Sequence: MDCSNGCSAE CTGEGGSKEV VGTFKAKDLI VTPATILKEK PDPNNLVFGT VFTDHMLTVE WSSEFGWEKP HIKPLQNLSL HPGSSALHYA VELFEGLKAF RGVDNKIRLF QPNLNMDRMY RSAVRATLPV FDKEELLECI QQLVKLDQEW VPYSTSASLY IRPTFIGTEP SLGVKKPTKA LLFVLLSPVG PYFSSGTFNP VSLWANPKYV RAWKGGTGDC KMGGNYGSSL FAQCEAVDNG CQQVLWLYGE DHQITEVGTM NLFLYWINED GEEELATPPL DGIILPGVTR RCILDLAHQW DTELSLFSIN LPDFLQFIYF
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: BCAT1 branched chain amino-acid transaminase 1, cytosolic [ Homo sapiens ]
• Official Symbol: BCAT1
• Synonyms: BCAT1; branched chain amino-acid transaminase 1, cytosolic; BCT1, branched chain aminotransferase 1, cytosolic; branched-chain-amino-acid aminotransferase, cytosolic; placental protein 18; branched chain aminotransferase 1, cytosolic; BCT1; PP18; BCATC; ECA39; MECA39; PNAS121; DKFZp686E12175
• Gene ID: 586
• mRNA Refseq: NM_001178091
• Protein Refseq: NP_001171562
• MIM: 113520
• UniProt ID: P54687