Recombinant Full Length Human BCL10 Protein, GST-tagged
Cat.No. : | BCL10-1579HF |
Product Overview : | Human BCL10 full-length ORF ( NP_003912.1, 1 a.a. - 233 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 52.7 kDa |
Protein Length : | 233 amino acids |
AA Sequence : | MEPTAPSLTE EDLTEVKKDA LENLRVYLCE KIIAERHFDH LRAKKILSRE DTEEISCRTS SRKRAGKLLD YLQENPKGLD TLVESIRREK TQNFLIQKIT DEVLKLRNIK LEHLKGLKCS SCEPFPDGAT NNLSRSNSDE SNFSEKLRAS TVMYHPEGES STTPFFSTNS SLNLPVLEVG RTENTIFSST TLPRPGDPGA PPLPPDLQLE EEGTCANSSE MFLPLRSRTV SRQ |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | BCL10 B-cell CLL/lymphoma 10 [ Homo sapiens ] |
Official Symbol : | BCL10 |
Synonyms : | BCL10; B-cell CLL/lymphoma 10; B-cell lymphoma/leukemia 10; c E10; CARD containing molecule enhancing NF kB; CARD containing apoptotic signaling protein; CARD containing proapoptotic protein; CARD like apoptotic protein; CARMEN; caspase recruiting domain containing protein; CIPER; CLAP; mE10; hCLAP; cCARMEN; cellular-E10; cellular homolog of vCARMEN; CARD-containing proapoptotic protein; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; caspase-recruiting domain-containing protein; CARD-containing molecule enhancing NF-kappa-B; mammalian CARD-containing adapter molecule E10; CED-3/ICH-1 prodomain homologous E10-like regulator; c-E10 |
Gene ID : | 8915 |
mRNA Refseq : | NM_003921 |
Protein Refseq : | NP_003912 |
MIM : | 603517 |
UniProt ID : | O95999 |
Products Types
◆ Recombinant Protein | ||
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BCL10-16H | Recombinant Human BCL10 Protein, His-tagged | +Inquiry |
BCL10-141H | Recombinant Human BCL10 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
BCL10-8490HCL | Recombinant Human BCL10 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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