Recombinant Full Length Human CAMLG Protein, GST-tagged
Cat.No. : | CAMLG-2794HF |
Product Overview : | Human CAMLG full-length ORF (NP_001736.1, 1 a.a. - 296 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 59.4 kDa |
Protein Length : | 296 amino acids |
AA Sequence : | MESMAVATDGGERPGVPAGSGLSAS QRRAELRRRKLLMNSEQRINRIMGF HRPGSGAEEESQTKSKQQDSDKLNS LSVPSVSKRVVLGDSVSTGTTDQQG GVAEVKGTQLGDKLDSFIKPPECSS DVNLELRQRNRGDLTADSVQRGSRH GLEQYLSRFEEAMKLRKQLISEKPS QEDGNTTEEFDSFRIFRLVGCALLA LGVRAFVCKYLSIFAPFLTLQLAYM GLYKYFPKSEKKIKTTVLTAALLLS GIPAEVINRSMDTYSKMGEVFTDLC VYFFTFIFCHELLDYWGSEVP |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CAMLG calcium modulating ligand [ Homo sapiens ] |
Official Symbol : | CAMLG |
Synonyms : | CAMLG; calcium modulating ligand; calcium signal-modulating cyclophilin ligand; calcium modulating cyclophilin ligand; calcium signal modulating cyclophilin ligand; CAML; cyclophilin B binding protein; cyclophilin B-binding protein; calcium-modulating cyclophilin ligand; calcium-signal modulating cyclophilin ligand; MGC163197; |
Gene ID : | 819 |
mRNA Refseq : | NM_001745 |
Protein Refseq : | NP_001736 |
MIM : | 601118 |
UniProt ID : | P49069 |
Products Types
◆ Recombinant Protein | ||
CAMLG-446R | Recombinant Rhesus Macaque CAMLG Protein, His (Fc)-Avi-tagged | +Inquiry |
CAMLG-0344H | Recombinant Human CAMLG Protein, GST-Tagged | +Inquiry |
Camlg-584R | Recombinant Rat Camlg Protein, His/GST-tagged | +Inquiry |
CAMLG-1202M | Recombinant Mouse CAMLG Protein, His (Fc)-Avi-tagged | +Inquiry |
CAMLG-582H | Recombinant Human CAMLG Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CAMLG-7872HCL | Recombinant Human CAMLG 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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