Recombinant Full Length Human CCNO Protein, GST-tagged

• Cat.No.: CCNO-2982HF
• Product Overview: Human CCNO full-length ORF (AAI60041.1, 1 a.a. - 350 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the cyclin protein family, and the encoded protein is involved in regulation of the cell cycle. Disruption of this gene is associated with primary ciliary dyskinesia-19. Alternative splicing results in multiple transcript variants. This gene, which has a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase in PubMed ID: 2001396. A later publication, PubMed ID: 8419333, identified this gene's product as a cyclin protein family member. The UNG2 symbol is also used as a specific protein isoform name for the UNG gene (GeneID 7374), so confusion exists in the scientific literature and in some databases for these two genes. [provided by RefSeq, Jul 2014]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 64.9 kDa
• Protein Length: 350 amino acids
• AA Sequence: MVTPCPTSPSSPAARAGRRDNDQNL RAPVKKSRRPRLRRKQPLHPLNPCP LPGDSGICDLFESPSSGSDGAESPS AARGGSPLPGPAQPVAQLDLQTFRD YGQSCYAFRKAQESHFHPREALARQ PQVTAESRCKLLSWLIPVHRQFGLS FESLCLTVNTLDRFLTTTPVAADCF QLLGVTSLLIACKQVEVHPPRVKQL LALCCGAFSRQQLCNLECIVLHKLH FTLGAPTISFFLEHFTHARVEAGQA EASEALEAQALARGVAELSLADYAF TSYSPSLLAICCLALADRMLRVSRP VDLRLGDHPEAALEDCMGKLQLLVA INSTSLTHMLPVQICEKCSLPPSSK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CCNO cyclin O [ Homo sapiens ]
• Official Symbol: CCNO
• Synonyms: CCNO; cyclin O; CCNU, cyclin U; cyclin-O; FLJ22422; UDG2; UNG2; cyclin U; cyclin domain containing; cyclin-like uracil-DNA glycosylase; CCNU
• Gene ID: 10309
• mRNA Refseq: NM_021147
• Protein Refseq: NP_066970
• MIM: 607752
• UniProt ID: P22674