Recombinant Full Length Human CENPN Protein, GST-tagged

• Cat.No.: CENPN-1720HF
• Product Overview: Human BM039 full-length ORF ( AAH07334, 1 a.a. - 204 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPN is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 48.18 kDa
• Protein Length: 204 amino acids
• AA Sequence: MDETVAEFIKRTILKIPMNELTTIL KAWDFLSENQLQTVNFRQRKESVVQ HLIHLCEEKRASISDAALLDIIYMQ FHQHQKVWDVFQMSKGPGEDVDLFD MKQFKNSFKKILQRALKNVTVSFRE TEENAVWIRIAWGTQYTKPNQYKPT YVVYYSQTPYAFTSSSMLRRNTPLL GQELEATGKIYLRQEEIILDITEMK KACN
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CENPN centromere protein N [ Homo sapiens ]
• Official Symbol: CENPN
• Synonyms: CENPN; centromere protein N; C16orf60, chromosome 16 open reading frame 60; BM039; FLJ13607; FLJ22660; interphase centromere complex protein 32; CENP-N; C16orf60
• Gene ID: 55839
• mRNA Refseq: NM_001100624
• Protein Refseq: NP_001094094
• MIM: 611509
• UniProt ID: Q96H22