| Description : |
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016] |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
66.1 kDa |
| Protein Length : |
458 amino acids |
| AA Sequence : |
MTLHNNSTTSPLFPNISSSWIHSPS DAGLPPGTVTHFGSYNVSRAAGNFS SPDGTTDDPLGGHTVWQVVFIAFLT GILALVTIIGNILVIVSFKVNKQLK TVNNYFLLSLACADLIIGVISMNLF TTYIIMNRWALGNLACDLWLAIDYV ASNASVMNLLVISFDRYFSITRPLT YRAKRTTKRAGVMIGLAWVISFVLW APAILFWQYFVGKRTVPPGECFIQF LSEPTITFGTAIAAFYMPVTIMTIL YWRIYKETEKRTKELAGLQASGTEA ETENFVHPTGSSRSCSSYELQQQSM KRSNRRKYGRCHFWFTTKSWKPSSE QMDQDHSSSDSWNNNDAAASLENSA SSDEEDIGSETRAIYSIVLKLPGHS TILNSTKLPSSDNLQVPEEELGMVD LERKADKLQAQKSVDDGGSFPKSFS KLPIQLESAVDTAKTSDVNSSVGKS TATLPLSFKEATLAKRFALKTRSQI TKRKRMSLVKEKKAAQTLSAILLAF IITWTPYNIMVLVNTFCDSCIPKTF WNLGYWLCYINSTVNPVCYALCNKT FRTTFKMLLLCQCDKKKRRKQQYQQ RQSVIFHKRAPEQAL |
| Applications : |
Antibody Production
Functional Study
Compound Screening |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
