Recombinant Full Length Human ciliary neurotrophic factor Protein, Tag Free

Species :	Human
Source :	HEK293
Tag :	Non
Protein Length :	1-200aa
Description :	The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
Tag :	Non
Molecular Mass :	23.3 kDa
Endotoxin :	Less than 1.0 EU/μg by the LAL method.
Purity :	>95% as determined by SDS-PAGE.
Storage :	Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Buffer :	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Reconstitution :	Reconstitute at 250 μg/mL in sterile water.

Gene Name	CNTF ciliary neurotrophic factor [ Homo sapiens (human) ]
Official Symbol	CNTF
Synonyms	CNTF; ciliary neurotrophic factor; HCNTF;
Gene ID	1270
mRNA Refseq	NM_000614
Protein Refseq	NP_000605
MIM	118945
UniProt ID	P26441