Recombinant Full Length Human COG5 Protein, GST-tagged

• Cat.No.: COG5-2083HF
• Product Overview: Human COG5 full-length ORF ( ADR82754.1, 1 a.a. - 823 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. The encoded protein is organized with conserved oligomeric Golgi complex components 6, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants. Mutations in this gene result in congenital disorder of glycosylation type 2I.[provided by RefSeq, Jan 2011]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 90.6 kDa
• Protein Length: 823 amino acids
• AA Sequence: MGWVGGRRRDSASPPGRSRSAADDI NPAPANMEGGGGSVAVAGLGARGSG AAAATVRELLQDGCYSDFLNEDFDV KTYTSQSIHQAVIAEQLAKLAQGIS QLDRELHLQVVARHEDLLAQATGIE SLEGVLQMMQTRIGALQGAVDRIKA KIVEPYNKIVARTAQLARLQVACDL LRRIIRILNLSKRLQGQLQGGSREI TKAAQSLNELDYLSQGIDLSGIEVI ENDLLFIARARLEVENQAKRLLEQG LETQNPTQVGTALQVFYNLGTLKDT ITSVVDGYCATLEENINSALDIKVL TQPSQSAVRGGPGRSTMPTPGNTAA LRASLWTNMEKLMDHIYAVCGQVQH LQKVLAKKRDPVSHICFIEEIVKDG QPEIFYTFWNSVTQALSSQFHMATN SSMFLKQAFEGEYPKLLRLYNDLWK RLQQYSQHIQGNFNASGTTDLYVDL QHMEDDAQDIFIPKKPDYDPEKALK DSLQPYEAAYLSKSLSRLFDPINLV FPPGGRNPPSSDELDGIIKTIASEL NVAAVDTNLTLAVSKNVAKTIQLYS VKSEQLLSTQGDASQVIGPLTEGQR RNVAVVNSLYKLHQSVTKVVSSQSS FPLAAEQTIISALKAIHALMENAVQ PLLTSVGDAIEAIIITMHQEDFSGS LSSSGKPDVPCSLYMKELQGFIARV MSDYFKHFECLDFVFDNTEAIAQRA VELFIRHASLIRPLGEGGKMRLAAD FAQMELAVGPFCRRVSDLGKSYRML RSFRPLLFQASEHVASSPALGDVIP FSIIIQFLFTRAPAELKSPFQRAEW SHTRFSQWLDDHPSEKDRLLLIR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: COG5 component of oligomeric golgi complex 5 [ Homo sapiens ]
• Official Symbol: COG5
• Synonyms: COG5; component of oligomeric golgi complex 5; golgi transport complex 1 (90 kDa subunit) , GOLTC1; conserved oligomeric Golgi complex subunit 5; GTC90; COG complex subunit 5; 13S golgi transport complex 1 90 kDa subunit; conserved oligomeric Golgi complex protein 5; CDG2I; GOLTC1; FLJ41732; FLJ44289
• Gene ID: 10466
• mRNA Refseq: NM_001161520
• Protein Refseq: NP_001154992
• MIM: 606821
• UniProt ID: Q9UP83