| Description : |
The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. The encoded protein is organized with conserved oligomeric Golgi complex components 6, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants. Mutations in this gene result in congenital disorder of glycosylation type 2I. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
94.7 kDa |
| AA Sequence : |
MGWVGGRRRDSASPPGRSRSAADDI NPAPANMEGGGGSVAVAGLGARGSG AAAATVRELLQDGCYSDFLNEDFDV KTYTSQSIHQAVIAEQLAKLAQGIS QLDRELHLQVVARHEDLLAQATGIE SLEGVLQMMQTRIGALQGAVDRIKA KIVEPYNKIVARTAQLARLQVACDL LRRIIRILNLSKRLQGQLQGGSREI TKAAQSLNELDYLSQGIDLSGIEVI ENDLLFIARARLEVENQAKRLLEQG LETQNPTQVGTALQVFYNLGTLKDT ITSVVDGYCATLEENINSALDIKVL TQPSQSAVRGGPGRSTMPTPGNTAA LRASLWTNMEKLMDHIYAVCGQVQH LQKVLAKKRDPVSHICFIEEIVKDG QPEIFYTFWNSVTQALSSQFHMATN SSMFLKQAFEGEYPKLLRLYNDLWK RLQQYSQHIQGNFNASGTTDLYVDL QHMEDDAQDIFIPKKPDYDPEKALK DSLQPYEAAYLSKSLSRLFDPINLV FPPGGRNPPSSDELDGIIKTIASEL NVAAVDTNLTLAVSKNVAKTIQLYS VKSEQLLSTQGDASQVIGPLTEGQR RNVAVVNSLYKLHQSVTKVVSSQSS FPLAAEQTIISALKAIHALMENAVQ PLLTSVGDAIEAIIITMHQEDFSGS LSSSGKPDVPCSLYMKELQGFIARV MSDYFKHFECLDFVFDNTEAIAQRA VELFIRHASLIRPLGEGGKMRLAAD FAQMELAVGPFCRRVSDLGKSYRML RSFRPLLFQASEHVASSPALGDVIP FSIIIQFLFTRAPAELKSPFQRAEW SHTRFSQWLDDHPSEKDRLLLIRGA LEAYVQSVRSREGKEFAPVYPIMVQ LLQKAMSALQTRTRPLEQKLISEED LAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
