| Description : |
The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011] |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
47.7 kDa |
| Protein Length : |
411 amino acids |
| AA Sequence : |
MDAALLHSLLEANCSLALAEELLLD GWGPPLDPEGPYSYCNTTLDQIGTC WPRSAAGALVERPCPEYFNGVKYNT TRNAYRECLENGTWASKINYSQCEP ILDDKQRKYDLHYRIALVVNYLGHC VSVAALVAAFLLFLALRSIRCLRNV IHWNLITTFILRNVMWFLLQLVDHE VHESNEVWCRCITTIFNYFVVTNFF WMFVEGCYLHTAIVMTYSTERLRKC LFLFIGWCIPFPIIVAWAIGKLYYE NEQCWFGKEPGDLVDYIYQGPIILV LLINFVFLFNIVRILMTKLRASTTS ETIQYRKAVKATLVLLPLLGITYML FFVNPGEDDLSQIMFIYFNSFLQSF QGFFVSVFYCFFNGEVRSAVRKRWH RWQDHHSLRVPMARAMSIPTSPTRI SFHSIKQTAAV |
| Applications : |
Antibody Production
Functional Study
Compound Screening |
| Usage : |
Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
