Recombinant Full Length Human CRNKL1 Protein, GST-tagged

• Cat.No.: CRNKL1-2087HF
• Product Overview: Human CRNKL1 full-length ORF ( NP_057736.4, 1 a.a. - 848 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. A protein encoded by this human locus has been found to localize to pre-mRNA splicing complexes in the nucleus and is necessary for pre-mRNA splicing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2013]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 119.68 kDa
• Protein Length: 848 amino acids
• AA Sequence: MTATVENLTFQKDTLGNAVDKNTSR LELRSYSLAGRHGSTEPLVLAWSSQ FRRLTWGCALDALHRSPCVAASQHG VTHLIRSSRTPHSTRCRKEDAQPGH HGNGAASVTAQARGQRSVLQVPLPV PRSCLFSESFVVSVSSQSRFLASVP GTGVQRSTAADMAASTAAGKQRIPK VAKVKNKAPAEVQITAEQLLREAKE RELELLPPPPQQKITDEEELNDYKL RKRKTFEDNIRKNRTVISNWIKYAQ WEESLKEIQRARSIYERALDVDYRN ITLWLKYAEMEMKNRQVNHARNIWD RAITTLPRVNQFWYKYTYMEEMLGN VAGARQVFERWMEWQPEEQAWHSYI NFELRYKEVDRARTIYERFVLVHPD VKNWIKYARFEEKHAYFAHARKVYE RAVEFFGDEHMDEHLYVAFAKFEEN QKEFERVRVIYKYALDRISKQDAQE LFKNYTIFEKKFGDRRGIEDIIVSK RRFQYEEEVKANPHNYDAWFDYLRL VESDAEAEAVREVYERAIANVPPIQ EKRHWKRYIYLWINYALYEELEAKD PERTRQVYQASLELIPHKKFTFAKM WILYAQFEIRQKNLSLARRALGTSI GKCPKNKLFKVYIELELQLREFDRC RKLYEKFLEFGPENCTSWIKFAELE TILGDIDRARAIYELAISQPRLDMP EVLWKSYIDFEIEQEETERTRNLYR RLLQRTQHVKVWISFAQFELSSGKE GSLTKCRQIYEEANKTMRNCEEKEE RLMLLESWRSFEEEFGTASDKERVD KLMPEKVKKRRKVQTDDGSDAGWEE YFDYIFPEDAANQPNLKLLAMAKLW KKQQQEKEDAEHHPDEDVDESES
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CRNKL1 crooked neck pre-mRNA splicing factor 1 [ Homo sapiens (human) ]
• Official Symbol: CRNKL1
• Synonyms: CRNKL1; crooked neck pre-mRNA splicing factor 1; Crooked Neck Pre-MRNA Splicing Factor 1; SYF3 Pre-MRNA-Splicing Factor; Crooked Neck Homolog; HCRN; CRN; Crooked Neck Pre-MRNA Splicing Factor-Like 1 (Drosophila); Crooked Neck (Drosophila Crn Homolog)-Like 1; Crooked Neck Pre-MRNA Splicing Factor-Like 1; Crn, Crooked Neck-Like 1 (Drosophila); Crooked Neck-Like Protein 1; Crn, Crooked Neck-Like 1; Crooked Neck-Like 1; MSTP021; Clf1; SYF3; CLF; crooked neck-like protein 1; Crn, crooked neck-like 1; SYF3 pre-mRNA-splicing factor; crooked neck homolog; crooked neck pre-mRNA splicing factor-like 1; crooked neck-like 1
• Gene ID: 51340
• mRNA Refseq: NM_001278625
• Protein Refseq: NP_001265554
• MIM: 610952
• UniProt ID: Q9BZJ0