Recombinant Full Length Human CYP27A1 Protein, C-Flag-tagged
Cat.No. : | CYP27A1-1332HFL |
Product Overview : | Recombinant Full Length Human CYP27A1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 56.9 kDa |
AA Sequence : | MAALGCARLRWALRGAGRGLCPHGA RAKAAIPAALPSDKATGAPGAGPGV RRRQRSLEEIPRLGQLRFFF QLFVQGYALQLHQLQVLYKAKYGPM WMSYLGPQMHVNLASAPLLEQVMRQ EGKYPVRNDMELWKEHRDQH DLTYGPFTTEGHHWYQLRQALNQRL LKPAEAALYTDAFNEVIDDFMTRLD QLRAESASGNQVSDMVQLFY YFALEAICYILFEKRIGCLQRSIPE DTVTFVRSIGLMFQNSLYATFLPKW TRPVLPFWKRYLDGWNAIFS FGKKLIDEKLEDMEAQLQAAGPDGI QVSGYLHFLLASGQLSPREAMGSLP ELLMAGVDTTSNTLTWALYH LSKDPEIQEALHEEVVGVVPAGQVP QHKDFAHMPLLKAVLKETLRLYPVV PTNSRIIEKEIEVDGFLFPK NTQFVFCHYVVSRDPTAFSEPESFQ PHRWLRNSQPATPRIQHPFGSVPFG YGVRACLGRRIAELEMQLLL ARLIQKYKVVLAPETGELKSVARIV LVPNKKVGLQFLQRQCTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, P450 |
Protein Pathways : | Metabolic pathways, PPAR signaling pathway, Primary bile acid biosynthesis |
Gene Name : | CYP27A1 cytochrome P450 family 27 subfamily A member 1 [ Homo sapiens (human) ] |
Official Symbol : | CYP27A1 |
Synonyms : | CTX; CP27; CYP27 |
Gene ID : | 1593 |
mRNA Refseq : | NM_000784.4 |
Protein Refseq : | NP_000775.1 |
MIM : | 606530 |
UniProt ID : | Q02318 |
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CYP27A1-1380R | Recombinant Rat CYP27A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CYP27A1-2131M | Recombinant Mouse CYP27A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CYP27A1-2253H | Recombinant Human CYP27A1 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
CYP27A1-7119HCL | Recombinant Human CYP27A1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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