Recombinant Full Length Human CYP3A5 Protein, GST-tagged
Cat.No. : | CYP3A5-2438HF |
Product Overview : | Human CYP3A5 full-length ORF ( AAH33862, 1 a.a. - 502 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 80.96 kDa |
Protein Length : | 502 amino acids |
AA Sequence : | MDLIPNLAVETWLLLAVSLVLLYLY GTRTHGLFKRLGIPGPTPLPLLGNV LSYRQGLWKFDTECYKKYGKMWGTY EGQLPVLAITDPDVIRTVLVKECYS VFTNRRSLGPVGFMKSAISLAEDEE WKRIRSLLSPTFTSGKLKEMFPIIA QYGDVLVRNLRREAEKGKPVTLKDI FGAYSMDVITGTSFGVNIDSLNNPQ DPFVESTKKFLKFGFLDPLFLSIIL FPFLTPVFEALNVSLFPKDTINFLS KSVNRMKKSRLNDKQKHRLDFLQLM IDSQNSKETESHKALSDLELAAQSI IFIFAGYETTSSVLSFTLYELATHP DVQQKLQKEIDAVLPNKAPPTYDAV VQMEYLDMVVNETLRLFPVAIRLER TCKKDVEINGVFIPKGSMVVIPTYA LHHDPKYWTEPEEFRPERFSKKKDS IDPYIYTPFGTGPRNCIGMRFALMN MKLALIRVLQNFSFKPCKETQIPLK LDTQGLLQPEKPIVLKVDSRDGTLS GE |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 [ Homo sapiens ] |
Official Symbol : | CYP3A5 |
Synonyms : | CYP3A5; cytochrome P450, family 3, subfamily A, polypeptide 5; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5; cytochrome P450 3A5; CP35; P450PCN3; PCN3; cytochrome P-450; niphedipine oxidase; cytochrome P450 HLp2; cytochrome P450-PCN3; microsomal monooxygenase; xenobiotic monooxygenase; aryl hydrocarbon hydroxylase; flavoprotein-linked monooxygenase; CYPIIIA5; FLJ31317; DKFZp686L16231; |
Gene ID : | 1577 |
mRNA Refseq : | NM_000777 |
Protein Refseq : | NP_000768 |
MIM : | 605325 |
UniProt ID : | P20815 |
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◆ Lysates | ||
CYP3A5-7106HCL | Recombinant Human CYP3A5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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