Recombinant Full Length Human DCT Protein, GST-tagged

• Cat.No.: DCT-2934HF
• Product Overview: Human DCT full-length ORF ( NP_001913.2, 1 a.a. - 519 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: DCT (Dopachrome Tautomerase) is a Protein Coding gene. Diseases associated with DCT include Microphthalmia and Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 1. Among its related pathways are Wnt Signaling Pathways: beta-Catenin-independent Wnt/Ca2+ Signaling and Other Non-canonical Wnt Signaling Pathways and Tyrosine metabolism. GO annotations related to this gene include oxidoreductase activity and dopachrome isomerase activity. An important paralog of this gene is TYRP1.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 85.5 kDa
• Protein Length: 519 amino acids
• AA Sequence: MSPLWWGFLLSCLGCKILPGAQGQF PRVCMTVDSLVNKECCPRLGAESAN VCGSQQGRGQCTEVRADTRPWSGPY ILRNQDDRELWPRKFFHRTCKCTGN FAGYNCGDCKFGWTGPNCERKKPPV IRQNIHSLSPQEREQFLGALDLAKK RVHPDYVITTQHWLGLLGPNGTQPQ FANCSVYDFFVWLHYYSVRDTLLGP GRPYRAIDFSHQGPAFVTWHRYHLL CLERDLQRLIGNESFALPYWNFATG RNECDVCTDQLFGAARPDDPTLISR NSRFSSWETVCDSLDDYNHLVTLCN GTYEGLLRRNQMGRNSMKLPTLKDI RDCLSLQKFDNPPFFQNSTFSFRNA LEGFDKADGTLDSQVMSLHNLVHSF LNGTNALPHSAANDPIFVVLHSFTD AIFDEWMKRFNPPADAWPQELAPIG HNRMYNMVPFFPPVTNEELFLTSDQ LGYSYAIDLPVSVEETPGWPTTLLV VMGTLVALVGLFVLLAFLQYRRLRK GYTPLMETHLSSKRYTEEA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DCT dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) [ Homo sapiens ]
• Official Symbol: DCT
• Synonyms: DCT; dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2); TYRP2; L-dopachrome tautomerase; DT; TRP2; dopachrome delta-isomerase; L-dopachrome Delta-isomerase; tyrosinase-related protein 2; TRP-2
• Gene ID: 1638
• mRNA Refseq: NM_001129889
• Protein Refseq: NP_001123361
• MIM: 191275
• UniProt ID: P40126