Recombinant Full Length Human DERL1 Protein, GST-tagged
Cat.No. : | DERL1-2474HF |
Product Overview : | Human DERL1 full-length ORF ( NP_077271.1, 1 a.a. - 251 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 55.2 kDa |
Protein length : | 251 amino acids |
AA Sequence : | MSDIGDWFRSIPAITRYWFAATVAV PLVGKLGLISPAYLFLWPEAFLYRF QIWRPITATFYFPVGPGTGFLYLVN LYFLYQYSTRLETGAFDGRPADYLF MLLFNWICIVITGLAMDMQLLMIPL IMSVLYVWAQLNRDMIVSFWFGTRF KACYLPWVILGFNYIIGGSVINELI GNLVGHLYFFLMFRYPMDLGGRNFL STPQFLYRWLPSRRGGVSGFGVPPA SMRRAADQNGGGGRHNWGQGFRLGD Q |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | DERL1 Der1-like domain family, member 1 [ Homo sapiens ] |
Official Symbol : | DERL1 |
Synonyms : | DERL1; Der1-like domain family, member 1; derlin-1; DER 1; DER1; derlin 1; FLJ13784; MGC3067; PRO2577; DERtrin-1; der1-like protein 1; degradation in endoplasmic reticulum protein 1; DER-1; FLJ42092; |
Gene ID : | 79139 |
mRNA Refseq : | NM_001134671 |
Protein Refseq : | NP_001128143 |
MIM : | 608813 |
UniProt ID : | Q9BUN8 |
Products Types
◆ Recombinant Protein | ||
DERL1-2336M | Recombinant Mouse DERL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DERL1-1069R | Recombinant Rhesus Macaque DERL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DERL1-2546H | Recombinant Human DERL1 Protein, GST-tagged | +Inquiry |
DERL1-1494C | Recombinant Chicken DERL1 | +Inquiry |
DERL1-12615Z | Recombinant Zebrafish DERL1 | +Inquiry |
◆ Lysates | ||
DERL1-6971HCL | Recombinant Human DERL1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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