Recombinant Full Length Human DGKA Protein, GST-tagged

• Cat.No.: DGKA-2496HF
• Product Overview: Human DGKA full-length ORF ( AAH31870, 1 a.a. - 735 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Several transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Apr 2017]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 106.37 kDa
• Protein Length: 735 amino acids
• AA Sequence: MAKERGLISPSDFAQLQKYMEYSTK KVSDVLKLFEDGEMAKYVQGDAIGY EGFQQFLKIYLEVDNVPRHLSLALF QSFETGHCLNETNVTKDVVCLNDVS CYFSLLEGGRPEDKLEFTFKLYDTD RNGILDSSEVDKIILQMMRVAEYLD WDVSELRPILQEMMKEIDYDGSGSV SQAEWVRAGATTVPLLVLLGLEMTL KDDGQHMWRPKRFPRPVYCNLCESS IGLGKQGLSCNLCKYTVHDQCAMKA LPCEVSTYAKSRKDIGVQSHVWVRG GCESGRCDRCQKKIRIYHSLTGLHC VWCHLEIHDDCLQAVGHECDCGLLR DHILPPSSIYPSVLASGPDRKNSKT SQKTMDDLNLSTSEALRIDPVPNTH PLLVFVNPKSGGKQGQRVLWKFQYI LNPRQVFNLLKDGPEIGLRLFKDVP DSRILVCGGDGTVGWILETIDKANL PVLPPVAVLPLGTGNDLARCLRWGG GYEGQNLAKILKDLEMSKVVHMDRW SVEVIPQQTEEKSDPVPFQIINNYF SIGVDASIAHRFYIMREKYPEKFNS RMKNKLWYFEFATSESIFSTCKKLE ESLTVEICGKPLDLSNLSLEGIAVL NIPSMHGGSNLWGDTRRPHGDIYGI NQALGATAKVITDPDILKTCVPDLS DKRLEVVGLEGAIEMGQIYTKLKNA GRRLAKCSEITFHTTKTLPMQIDGE PWVQTPCTIKITHKNQMPMLMGPPP RSTNFFGFLS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DGKA diacylglycerol kinase, alpha 80kDa [ Homo sapiens ]
• Official Symbol: DGKA
• Synonyms: DGKA; diacylglycerol kinase, alpha 80kDa; DAGK, DAGK1, diacylglycerol kinase, alpha (80kD); diacylglycerol kinase alpha; DGK alpha; DAG kinase alpha; diglyceride kinase alpha; 80 kDa diacylglycerol kinase; DAGK; DAGK1; DGK-alpha; MGC12821; MGC42356
• Gene ID: 1606
• mRNA Refseq: NM_001345
• Protein Refseq: NP_001336
• MIM: 125855
• UniProt ID: P23743