| Species : |
Human |
| Source : |
In Vitro Cell Free System |
| Protein Length : |
1049 amino acids |
| Description : |
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. |
| Form : |
Liquid |
| Molecular Mass : |
142.390kDa inclusive of tags |
| AA Sequence : |
MDWSFFRVVAMLFIFLVVVEVNSEFRIQVRDYNTKNGTIK WHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAAN QQVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVT PFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMA TFAGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIR QEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGS DRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQE NTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEI EMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHS IMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGS NDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTG KLTLKNKVTKEQYNMLGGKYQGTILSIDDNLQRTCTGTIN INIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTT STDSSQVYSSEPGNGAKDLLSDNVHFGPAGIGLLIMGFLV LGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVE GPQPEPRDITTVIPQIPPDNANIIECIDNSGVYTNEYGGR EMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNS MRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLI YDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLAD ISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPIS PHFGTTTVISESTYPSGPGVLHPKPILDPLGYGNVTVTES YTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGM LEMPDLRDGSNVIVTERVIAPSSSLPTSLTIHHPRESSNV VVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAG VTGISGTTGISGGIGSSGLVGTSMGAGSGALSGAGISGGG IGLSSLGGTASIGHMRSSSDHHFNQTIGSASPSTARSRIT KYSTVQYSK |
| Purity : |
Proprietary Purification |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
| Storage Buffer : |
pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
