Recombinant Full Length Human DUS2L Protein, GST-tagged

• Cat.No.: DUS2L-4886HF
• Product Overview: Human FLJ20399 full-length ORF ( AAH06527, 1 a.a. - 493 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Dihydrouridine synthase catalyzes reduction of the 5,6-double bond of a uridine residue on the displacement loop of tRNA. The resultant modified base, 5,6-dihydrouridine, appears to increase the conformational flexibility and dynamic motion of tRNA (Kato et al., 2005 [PubMed 15994936]).[supplied by OMIM
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 79.97 kDa
• Protein Length: 493 amino acids
• AA Sequence: MILNSLSLCYHNKLILAPMVRVGTL PMRLLALDYGADIVYCEELIDLKMI QCKRVVNEVLSTVDFVAPDDRVVFR TCEREQNRVVFQMGTSDAERALAVA RLVENDVAGIDVNMGCPKQYSTKGG MGAALLSDPDKIEKILSTLVKGTRR PVTCKIRILPSLEDTLSLVKRIERT GIAAIAVHGRKREERPQHPVSCEVI KAIADTLSIPVIANGGSHDHIQQYS DIEDFRQATAASSVMVARAAMWNPS IFLKEGLRPLEEVMQKYIRYAVQYD NHYTNTKYCLCQMLREQLESPQGRL LHAAQSSREICEAFGLGAFYEETTQ ELDAQQARLSAKTSEQTGEPAEDTS GVIKMAVKFDRRAYPAQITPKMCLL EWCRREKLAQPVYETVQRPLDRLFS SIVTVAEQKYQSTLWDKSKKLAEQA AAIVCLRSQGLPEGRLGEESPSLHK RKREAPDQDPGGPRAQELAQPGDLC KKPFVALGSGEESPLEGW
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DUS2L dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: DUS2L
• Synonyms: DUS2L; dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae); dihydrouridine synthase 2 like (SMM1, S. cerevisiae); tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; DUS2; FLJ20399; SMM1; hDUS2; up-regulated in lung cancer 8; up-regulated in lung cancer protein 8; URLC8
• Gene ID: 54920
• mRNA Refseq: NM_017803
• Protein Refseq: NP_060273
• MIM: 609707
• UniProt ID: Q9NX74