Recombinant Full Length Human EML1 Protein, GST-tagged

• Cat.No.: EML1-4244HF
• Product Overview: Human EML1 full-length ORF ( AAH33043.1, 1 a.a. - 815 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 115.39 kDa
• Protein Length: 815 amino acids
• AA Sequence: MEDGFSSYSSLYDTSSLLQFCNDDS ASAASSMEVTDRIASLEQRVQMQED DIQLLKSALADVVRRLNITEEQQAV LNRKGPTKARPLMQTLPLRTTVNNG TVLPKKPTGSLPSPSGVRKETAVPA TKSNIKRTSSSERVSPGGRRESNGD SRGNRNRTGSTSSSSSGKKNSESKP KEPVFSAEEGYVKMFLRGRPVTMYM PKDQVDSYSLEAKVELPTKRLKLEW VYGYRGRDCRNNLYLLPTGETVYFI ASVVVLYNVEEQLQRHYAGHNDDVK CLAVHPDRITIATGQVAGTSKDGKQ LPPHVRIWDSVTLNTLHVIGIGFFD RAVTCIAFSKSNGGTNLCAVDDSND HVLSVWDWQKEEKLADVKCSNEAVF AADFHPTDTNIIVTCGKSHLYFWTL EGSSLNKKQGLFEKQEKPKFVLCVT FSENGDTITGDSSGNILVWGKGTNR ISYAVQGAHEGGIFALCMLRDGTLV SGGGKDRKLISWSGNYQKLRKTEIP EQFGPIRTVAEGKGDVILIGTTRNF VLQGTLSGDFTPITQGHTDELWGLA INASKSQFLTCGHDKHATLWDAVGH RPVWDKIIEDPAQSSGFHPSGSVVA VGTLTGRWFVFDTGTKDLVTVHTDG NEQLSVMRYSPDGNFLAIGSHDNCI YIYGVSDNGRKYTRVGKCSGHSSFI THLDWSVNSQFLVSNSGDYEILYWV PSACKQVVSVETTRDIEWATYTCTL GFHVFGVWPEGSDGTDINAVCRAHE KKLLSTGDDFGKVHLFSYPCSQFRA PSHIYGGHSSHVTNVDFLCEDSHLI STGGKDTSIMQWRVI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EML1 echinoderm microtubule associated protein like 1 [ Homo sapiens ]
• Official Symbol: EML1
• Synonyms: EML1; echinoderm microtubule associated protein like 1; EMAPL; echinoderm microtubule-associated protein-like 1; ELP79; EMAP; HuEMAP; EMAP-1; huEMAP-1; FLJ45033
• Gene ID: 2009
• mRNA Refseq: NM_001008707
• Protein Refseq: NP_001008707
• MIM: 602033
• UniProt ID: O00423