Recombinant Full Length Human ETFA Protein, GST-tagged

• Cat.No.: ETFA-4732HF
• Product Overview: Human ETFA full-length ORF ( AAH15526, 1 a.a. - 333 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 62.37 kDa
• Protein Length: 333 amino acids
• AA Sequence: MFRAAAPGQLRRAASLLRFQSTLVI AEHANDSLAPITLNTITAATRLGGE VSCLVAGTKCDKVAQDLCKVAGIAK VLVAQHDVYKGLLPEELTPLILATQ KQFNYTHICAGASAFGKNLLPRVAA KLEVAPISDIIAIKSPDTFVRTIYA GNALCTVKCDEKVKVFSVRGTSFDA AATSGGSASSEKASSTSPVEISEWL DQKLTKSDRPELTGAKVVVSGGRGL KSGENFKLLYDLADQLHAAVGASRA AVDAGFVPNDMQVGQTGKIVAPELY IAVGISGAIQHLAGMKDSKTIVAIN KDPEAPIFQVADYGIVADLFKVVPE MTEILKKK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ETFA electron-transfer-flavoprotein, alpha polypeptide [ Homo sapiens ]
• Official Symbol: ETFA
• Synonyms: ETFA; electron-transfer-flavoprotein, alpha polypeptide; electron transfer flavoprotein subunit alpha, mitochondrial; EMA; GA2; glutaric aciduria II; MADD; alpha-ETF; electron transfer flavoprotein alpha-subunit; electron transfer flavoprotein, alpha polypeptide
• Gene ID: 2108
• mRNA Refseq: NM_000126
• Protein Refseq: NP_000117
• MIM: 608053
• UniProt ID: P13804