Recombinant Full Length Human EXTL3 Protein, GST-tagged

• Cat.No.: EXTL3-4455HF
• Product Overview: Human EXTL3 full-length ORF ( NP_001431.1, 1 a.a. - 919 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. [provided by RefSeq, Nov 2012]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 131.1 kDa
• Protein Length: 919 amino acids
• AA Sequence: MTGYTMLRNGGAGNGGQTCMLRWSN RIRLTWLSFTLFVILVFFPLIAHYY LTTLDEADEAGKRIFGPRVGNELCE VKHVLDLCRIRESVSEELLQLEAKR QELNSEIAKLNLKIEACKKSIENAK QDLLQLKNVISQTEHSYKELMAQNQ PKLSLPIRLLPEKDDAGLPPPKATR GCRLHNCFDYSRCPLTSGFPVYVYD SDQFVFGSYLDPLVKQAFQATARAN VYVTENADIACLYVILVGEMQEPVV LRPAELEKQLYSLPHWRTDGHNHVI INLSRKSDTQNLLYNVSTGRAMVAQ STFYTVQYRPGFDLVVSPLVHAMSE PNFMEIPPQVPVKRKYLFTFQGEKI ESLRSSLQEARSFEEEMEGDPPADY DDRIIATLKAVQDSKLDQVLVEFTC KNQPKPSLPTEWALCGEREDRLELL KLSTFALIITPGDPRLVISSGCATR LFEALEVGAVPVVLGEQVQLPYQDM LQWNEAALVVPKPRVTEVHFLLRSL SDSDLLAMRRQGRFLWETYFSTADS IFNTVLAMIRTRIQIPAAPIREEAA AEIPHRSGKAAGTDPNMADNGDLDL GPVETEPPYASPRYLRNFTLTVTDF YRSWNCAPGPFHLFPHTPFDPVLPS EAKFLGSGTGFRPIGGGAGGSGKEF QAALGGNVPREQFTVVMLTYEREEV LMNSLERLNGLPYLNKVVVVWNSPK LPSEDLLWPDIGVPIMVVRTEKNSL NNRFLPWNEIETEAILSIDDDAHLR HDEIMFGFRVWREARDRIVGFPGRY HAWDIPHQSWLYNSNYSCELSMVLT GAAFFHKYYAYLYSYVMPQAIRDMV DEYINCEDIAMNFLVSHITRKPPIK VTSRWTFRCPGCPQALSHDDSHFHE RHKCINFFVKVYGYMPLLYTQFRVD SVLFKTRLPHDKTKCFKFI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EXTL3 exostoses (multiple)-like 3 [ Homo sapiens ]
• Official Symbol: EXTL3
• Synonyms: EXTL3; exostoses (multiple)-like 3; exostosin-like 3; botv; REG receptor; REGR; reg receptor; EXT-related protein 1; multiple exostosis-like protein 3; putative tumor suppressor protein EXTL3; hereditary multiple exostoses gene isolog; glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; REG; RPR; BOTV; EXTR1; KIAA0519; DKFZp686C2342
• Gene ID: 2137
• mRNA Refseq: NM_001440
• Protein Refseq: NP_001431
• MIM: 605744
• UniProt ID: O43909