Recombinant Full Length Human FGL1 Protein, C-Flag-tagged

• Cat.No.: FGL1-184HFL
• Product Overview: Recombinant Full Length Human FGL1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 34 kDa
• AA Sequence: MAKVFSFILVTTALTMGREISALED CAQEQMRLRAQVRLLETRVKQQQVK IKQLLQENEVQFLDKGDENT VIDLGSKRQYADCSEIFNDGYKLSG FYKIKPLQSPAEFSVYCDMSDGGGW TVIQRRSDGSENFNRGWKDY ENGFGNFVQKHGEYWLGNKNLHFLT TQEDYTLKIDLADFEKNSRYAQYKN FKVGDEKNFYELNIGEYSGT AGDSLAGNFHPEVQWWASHQRMKFS TWDRDHDNYEGNCAEEDQSGWWFNR CHSANLNGVYYSGPYTAKTD
  NGIVWYTWHGWWYSLKSVVMKIRPN DFIPNVITRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein

Gene Information

• Gene Name: FGL1 fibrinogen like 1 [ Homo sapiens (human) ]
• Official Symbol: FGL1
• Synonyms: HPS; HFREP1; HP-041; LFIRE1; LFIRE-1
• Gene ID: 2267
• mRNA Refseq: NM_004467.4
• Protein Refseq: NP_004458.3
• MIM: 605776
• UniProt ID: Q08830