Recombinant Full Length Human FMR1 Protein, GST-tagged

• Cat.No.: FMR1-4996HF
• Product Overview: Human FMR1 full-length ORF ( AAH38998.1, 1 a.a. - 297 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5 UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). [provided by RefSeq
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 58.41 kDa
• Protein Length: 297 amino acids
• AA Sequence: MEELVVEVRGSNGAFYKAFVKDVHE DSITVAFENNWQPDRQIPFHDVRFP PPVGYNKDINESDEVEVYSRANEKE PCCWWLAKVRMIKGEFYVIEYAACD ATYNEIVTIERLRSVNPNKPATKDT FHKIKLDVPEDLRQMCAKEAAHKDF KKAVGAFSVTYDPENYQLVILSINE VTSKRAHMLIDMHFRSLRTKLSLIM RNEEASKQLESSRQLASRFHEQFIV REDLMGLAIGTHGANIQQARKVPGV TAIDLDEDTCTFHIYGEDQDAVKKA RSFLEFAEDVIQVPRNLVGLKI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FMR1 fragile X mental retardation 1 [ Homo sapiens ]
• Official Symbol: FMR1
• Synonyms: FMR1; fragile X mental retardation 1; POF, POF1, premature ovarian failure 1; fragile X mental retardation protein 1; FMRP; FRAXA; MGC87458; protein FMR-1; fragile X mental retardation 1 protein; POF; POF1
• Gene ID: 2332
• mRNA Refseq: NM_001185075
• Protein Refseq: NP_001172004
• MIM: 309550
• UniProt ID: Q06787