Recombinant Full Length Human GAD1 Protein, GST-tagged
Cat.No. : | GAD1-5204HF |
Product Overview : | Human GAD1 full-length ORF ( AAH26349, 1 a.a. - 594 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 91.08 kDa |
Protein Length : | 594 amino acids |
AA Sequence : | MASSTPSSSATSSNAGADPNTTNLR PTTYDTWCGVAHGCTRKLGLKICGF LQRTNSLEEKSRLVSAFKERQSSKN LLSCENSDRDARFRRTETDFSNLFA RDLLPAKNGEEQTVQFLLEVVDILL NYVRKTFDRSTKVLDFHHPHQLLEG MEGFNLELSDHPESLEQILVDCRDT LKYGVRTGHPRFFNQLSTGLDIIGL AGEWLTSTANTNMFTYEIAPVFVLM EQITLKKMREIVGWSSKDGDGIFSP GGAISNMYSIMAARYKYFPEVKTKG MAAVPKLVLFTSEQSHYSIKKAGAA LGFGTDNVILIKCNERGKIIPADFE AKILEAKQKGYVPFYVNATAGTTVY GAFDPIQEIADICEKYNLWLHVDAA WGGGLLMSRKHRHKLNGIERANSVT WNPHKMMGVLLQCSAILVKEKGILQ GCNQMCAGYLFQPDKQYDVSYDTGD KAIQCGRHVDIFKFWLMWKAKGTVG FENQINKCLELAEYLYAKIKNREEF EMVFNGEPEHTNVCFWYIPQSLRGV PDSPQRREKLHKVAPKIKALMMESG TTMVGYQPQGDKANFFRMVISNPAA TQSDIDFLIEEIERLGQDL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GAD1 glutamate decarboxylase 1 (brain, 67kDa) [ Homo sapiens ] |
Official Symbol : | GAD1 |
Synonyms : | GAD1; glutamate decarboxylase 1 (brain, 67kDa); GAD, glutamate decarboxylase 1 (brain, 67kD); glutamate decarboxylase 1; GAD-67; 67 kDa glutamic acid decarboxylase; glutamate decarboxylase 67 kDa isoform; GAD; SCP; CPSQ1; FLJ45882; |
Gene ID : | 2571 |
mRNA Refseq : | NM_000817 |
Protein Refseq : | NP_000808 |
MIM : | 605363 |
UniProt ID : | Q99259 |
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◆ Lysates | ||
GAD1-586HCL | Recombinant Human GAD1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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