Recombinant Full Length Human GCLM Protein, C-Flag-tagged
Cat.No. : | GCLM-1237HFL |
Product Overview : | Recombinant Full Length Human GCLM Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 30.5 kDa |
AA Sequence : | MGTDSRAAKALLARARTLHLQTGNL LNWGRLRKKCPSTHSEELHDCIQKT LNEWSSQINPDLVREFPDVL ECTVSHAVEKINPDEREEMKVSAKL FIVESNSSSSTRSAVDMACSVLGVA QLDSVIIASPPIEDGVNLSL EHLQPYWEELENLVQSKKIVAIGTS DLDKTQLEQLYQWAQVKPNSNQVNL ASCCVMPPDLTAFAKQFDIQ LLTHNDPKELLSEASFQEALQESIP DIQAHEWVPLWLLRYSVIVKSRGII KSKGYILQAKRRGSTRTRPLEQKLI SEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Glutathione metabolism, Metabolic pathways |
Gene Name : | GCLM glutamate-cysteine ligase modifier subunit [ Homo sapiens (human) ] |
Official Symbol : | GCLM |
Synonyms : | GLCLR |
Gene ID : | 2730 |
mRNA Refseq : | NM_002061.4 |
Protein Refseq : | NP_002052.1 |
MIM : | 601176 |
UniProt ID : | P48507 |
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◆ Lysates | ||
GCLM-5982HCL | Recombinant Human GCLM 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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