Recombinant Full Length Human GNRHR Protein
Cat.No. : | GNRHR-5412HF |
Product Overview : | Human GNRHR full-length ORF (ADR83139.1) recombinant protein without tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5 region and multiple polyA signals in the 3 region have been identified for this gene. [provided by RefSeq |
Source : | In Vitro Cell Free System |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 36.1 kDa |
Protein Length : | 379 amino acids |
AA Sequence : | MANSASPEQNQNHCSAINNSIPLMQ GNLPTLTLSGKIRVTVTFFLFLLSA TFNASFLLKLQKWTQKKEKGKKLSR MKLLLKHLTLANLLETLIVMPLDGM WNITVQWYAGELLCKVLSYLKLFSM YAPAFMMVVISLDRSLAITRPLALK SNSKVGQSMVGLAWILSSVFAGPQL YIFRMIHLADSSGQTKVFSQCVTHC SFSQWWHQAFYNFFTFSCLFIIPLF IMLICNAKIIFTLTRVLHQDPHELQ LNQSKNNIPRARLKTLKMTVAFATS FTVCWTPYYVLGIWYWFDPEMLNRL SDPVNHFFFLFAFLNPCFDPLIYGY FSL |
Applications : | Antibody Production Functional Study Compound Screening |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
Gene Name : | GNRHR gonadotropin-releasing hormone receptor [ Homo sapiens ] |
Official Symbol : | GNRHR |
Synonyms : | GNRHR; gonadotropin-releasing hormone receptor; GRHR; LHRHR; gnRH-R; gnRH receptor; luliberin receptor; type I GnRH receptor; leutinizing-releasing hormone receptor; leutinizing hormone releasing horomone receptor; gonadotropin-releasing hormone (type 1) receptor 1; LRHR; GNRHR1; |
Gene ID : | 2798 |
mRNA Refseq : | NM_000406 |
Protein Refseq : | NP_000397 |
MIM : | 138850 |
UniProt ID : | P30968 |
Products Types
◆ Recombinant Protein | ||
GNRHR-2270R | Recombinant Rat GNRHR Protein, His (Fc)-Avi-tagged | +Inquiry |
GNRHR-3788M | Recombinant Mouse GNRHR Protein, His (Fc)-Avi-tagged | +Inquiry |
GNRHR-5099H | Recombinant Human GNRHR Protein | +Inquiry |
GNRHR-7056M | Recombinant Mouse GNRHR Protein | +Inquiry |
GNRHR-1044HFL | Recombinant Human GNRHR protein, His&Flag-tagged | +Inquiry |
◆ Lysates | ||
GNRHR-5837HCL | Recombinant Human GNRHR 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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