Recombinant Full Length Human GPT2 Protein, C-Flag-tagged
Cat.No. : | GPT2-1258HFL |
Product Overview : | Recombinant Full Length Human GPT2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 57.7 kDa |
AA Sequence : | MQRAAALVRRGCGPRTPSSWGRSQS SAAAEASAVLKVRPERSRRERILTL ESMNPQVKAVEYAVRGPIVL KAGEIELELQRGIKKPFTEVIRANI GDAQAMGQQPITFLRQVMALCTYPN LLDSPSFPEDAKKRARRILQ ACGGNSLGSYSASQGVNCIREDVAA YITRRDGGVPADPDNIYLTTGASDG ISTILKILVSGGGKSRTGVM IPIPQYPLYSAVISELDAIQVNYYL DEENCWALNVNELRRAVQEAKDHCD PKVLCIINPGNPTGQVQSRK CIEDVIHFAWEEKLFLLADEVYQDN VYSPDCRFHSFKKVLYEMGPEYSSN VELASFHSTSKGYMGECGYR GGYMEVINLHPEIKGQLVKLLSVRL CPPVSGQAAMDIVVNPPVAGEESFE QFSREKESVLGNLAKKAKLT EDLFNQVPGIHCNPLQGAMYAFPRI FIPAKAVEAAQAHQMAPDMFYCMKL LEETGICVVPGSGFGQREGT YHFRMTILPPVEKLKTVLQKVKDFH INFLEKYASGPTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Pathways : | Alanine, aspartate and glutamate metabolism, Metabolic pathways |
Gene Name : | GPT2 glutamic--pyruvic transaminase 2 [ Homo sapiens (human) ] |
Official Symbol : | GPT2 |
Synonyms : | ALT2; GPT 2; MRT49; NEDSPM |
Gene ID : | 84706 |
mRNA Refseq : | NM_133443.4 |
Protein Refseq : | NP_597700.1 |
MIM : | 138210 |
UniProt ID : | Q8TD30 |
Products Types
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◆ Lysates | ||
GPT2-720RCL | Recombinant Rat GPT2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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