Recombinant Full Length Human GUCY1A3 Protein, GST-tagged

• Cat.No.: GUCY1A3-3345HF
• Product Overview: Human GUCY1A3 full-length ORF ( AAH28384.1, 1 a.a. - 690 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit, such as alpha-1 (GUCY1A3), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 103.9 kDa
• Protein Length: 690 amino acids
• AA Sequence: MFCTKLKDLKITGECPFSLLAPGQV PNESSEEAAGSSESCKATMPICQDI PEKNIQESLPQRKTSRSRVYLHTLA ESICKLIFPEFERLNVALQRTLAKH KIKESRKSLEREDFEKTIAEQAVAA GVPVEVIKESLGEEVFKICYEEDEN ILGVVGGTLKDFLNSFSTLLKQSSH CQEAGKRGRLEDASILCLDKEDDFL HVYYFFPKRTTSLILPGIIKAAAHV LYETEVEVSLMPPCFHNDCSEFVNQ PYLLYSVHMKSTKPSLSPSKPQSSL VIPTSLFCKTFPFHFMFDKDMTILQ FGNGIRRLMNRRDFQGKPNFEEYFE ILTPKINQTFSGIMTMLNMQFVVRV RRWDNSVKKSSRVMDLKGQMIYIVE SSAILFLGSPCVDRLEDFTGRGLYL SDIPIHNALRDVVLIGEQARAQDGL KKRLGKLKATLEQAHQALEEEKKKT VDLLCSIFPCEVAQQLWQGQVVQAK KFSNVTMLFSDIVGFTAICSQCSPL QVITMLNALYTRFDQQCGELDVYKV ETIGDAYCVAGGLHKESDTHAVQIA LMAVKMMELSDEVMSPHGEPIKMRI GLHSGSVFAGVVGVKMPRYCLFGNN VTLANKFESCSVPRKINVSPTTYRL LKDCPGFVFTPRSREELPPNFPSEI PGICHFLDAYQQGTNSKPCFQKKDV EDGNANFLGKASGID
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GUCY1A3 guanylate cyclase 1, soluble, alpha 3 [ Homo sapiens ]
• Official Symbol: GUCY1A3
• Synonyms: GUCY1A3; guanylate cyclase 1, soluble, alpha 3; GUC1A3; guanylate cyclase soluble subunit alpha-3; GC SA3; GCS-alpha-1; GCS-alpha-3; GC-S-alpha-1; soluble guanylate cyclase large subunit; GUCA3; GC-SA3; GUCSA3; GUCY1A1
• Gene ID: 2982
• mRNA Refseq: NM_000856
• Protein Refseq: NP_000847
• MIM: 139396
• UniProt ID: Q02108