| Description : |
This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. There are many pseudogenes of this locus in the human genome. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
95.410kDa inclusive of tags |
| Protein Length : |
630 amino acids |
| AA Sequence : |
GLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFEE QWYRRPLWESGPTVDMPVPSSFNDISQDWRLRHFVGWVWY EREVILPERWTQDLRTRVVLRIGSAHSYAIVWVNGVDTLE HEGGYLPFEADISNLVQVGPLPSRLRITIAINNTLTPTTL PPGTIQYLTDTSKYPKGYFVQNTYFDFFNYAGLQRSVLLY TTPTTYIDDITVTTSVEQDSGLVNYQISVKGSNLFKLEVR LLDAENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYLY SLEVQLTAQTSLGPVSDFYTLPVGIRTVAVTKSQFLINGK PFYFHGVNKHEDADIRGKGFDWPLLVKDFNLLRWLGANAF RTSHYPYAEEVMQMCDRYGIVVIDECPGVGLALPQFFNNV SLHHHMQVMEEVVRRDKNHPAVVMWSVANEPASHLESAGY YLKMVIAHTKSLDPSRPVTFVSNSNYAADKGAPYVDVICL NSYYSWYHDYGHLELIQLQLATQFENWYKKYQKPIIQSEY GAETIAGFHQDPPLMFTEEYQKSLLEQYHLGLDQKRRKYV VGELIWNFADFMTEQSPTRVLGNKKGIFTRQRQPKSAAFL LRERYWKIANETRYPHSVAKSQCLENSLFT |
| Purity : |
Proprietary Purification |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
| Storage Buffer : |
pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
