Recombinant Full Length Human HEPH Protein, C-Flag-tagged

• Cat.No.: HEPH-902HFL
• Product Overview: Recombinant Full Length Human HEPH Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the multicopper oxidase protein family. The encoded protein is involved in the transport of dietary iron from epithelial cells of the intestinal lumen into the circulatory system, and may be involved in copper transport and homeostasis. In mouse, defects in this gene can lead to severe microcytic anemia. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 136.5 kDa
• AA Sequence: MESGHLLWALLFMQSLWPQLTDGAT RVYYLGIRDVQWNYAPKGRNVITNQ PLDSDIVASSFLKSDKNRIG GTYKKTIYKEYKDDSYTDEVAQPAW LGFLGPVLQAEVGDVILIHLKNFAT RPYTIHPHGVFYEKDSEGSL YPDGSSGPLKADDSVPPGGSHIYNW TIPEGHAPTDADPACLTWIYHSHVD APRDIATGLIGPLITCKRGA LDGNSPPQRQDVDHDFFLLFSVVDE NLSWHLNENIATYCSDPASVDKEDE TFQESNRMHAINGFVFGNLP ELNMCAQKRVAWHLFGMGNEIDVHT AFFHGQMLTTRGHHTDVANIFPATF VTAEMVPWEPGTWLISCQVN SHFRDGMQALYKVKSCSMAPPVDLL TGKVRQYFIEAHEIQWDYGPMGHDG STGKNLREPGSISDKFFQKS SSRIGGTYWKVRYEAFQDETFQEKM HLEEDRHLGILGPVIRAEVGDTIQV VFYNRASQPFSMQPHGVFYE KDYEGTVYNDGSSYPGLVAKPFEKV TYRWTVPPHAGPTAQDPACLTWMYF SAADPIRDTNSGLVGPLLVC RAGALGADGKQKGVDKEFFLLFTVL DENKSWYSNANQAAAMLDFRLLSED IEGFQDSNRMHAINGFLFSN LPRLDMCKGDTVAWHLLGLGTETDV HGVMFQGNTVQLQGMRKGAAMLFPH TFVMAIMQPDNLGTFEIYCQ AGSHREAGMRAIYNVSQCPGHQATP RQRYQAARIYYIMAEEVEWDYCPDR SWEREWHNQSEKDSYGYIFL SNKDGLLGSRYKKAVFREYTDGTFR IPRPRTGPEEHLGILGPLIKGEVGD ILTVVFKNNASRPYSVHAHG VLESTTVWPLAAEPGEVVTYQWNIP ERSGPGPNDSACVSWIYYSAVDPIK DMYSGLVGPLAICQKGILEP HGGRSDMDREFALLFLIFDENKSWY LEENVATHGSQDPGSINLQDETFLE SNKMHAINGKLYANLRGLTM YQGERVAWYMLAMGQDVDLHTIHFH AESFLYRNGENYRADVVDLFPGTFE VVEMVASNPGTWLMHCHVTD HVHAGMETLFTVFSRTEHLSPLTVI TKETEKAVPPRDIEEGNVKMLGMQI PIKNVEMLASVLVAISVTLL
  LVVLALGGVVWYQHRQRKLRRNRRS ILDDSFKLLSFKQTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane

Gene Information

• Gene Name: HEPH hephaestin [ Homo sapiens (human) ]
• Official Symbol: HEPH
• Synonyms: CPL
• Gene ID: 9843
• mRNA Refseq: NM_138737.6
• Protein Refseq: NP_620074.4
• MIM: 300167
• UniProt ID: Q9BQS7