Recombinant Full Length Human HGS Protein, GST-tagged

• Cat.No.: HGS-3537HF
• Product Overview: Human HGS full-length ORF ( NP_004703.1, 1 a.a. - 777 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 112.6 kDa
• Protein Length: 777 amino acids
• AA Sequence: MGRGSGTFERLLDKATSQLLLETDW ESILQICDLIRQGDTQAKYAVNSIK KKVNDKNPHVALYALEVMESVVKNC GQTVHDEVANKQTMEELKDLLKRQV EVNVRNKILYLIQAWAHAFRNEPKY KVVQDTYQIMKVEGHVFPEFKESDA MFAAERAPDWVDAEECHRCRVQFGV MTRKHHCRACGQIFCGKCSSKYSTI PKFGIEKEVRVCEPCYEQLNRKAEG KATSTTELPPEYLTSPLSQQSQLPP KRDETALQEEEELQLALALSQSEAE EKERLRQKSTYTSYPKAEPMPSASS APPASSLYSSPVNSSAPLAEDIDPE LARYLNRNYWEKKQEEARKSPTPSA PVPLTEPAAQPGEGHAAPTNVVENP LPETDSQPIPPSGGPFSEPQFHNGE SEESHEQFLKALQNAVTTFVNRMKS NHMRGRSITNDSAVLSLFQSINGMH PQLLELLNQLDERRLYYEGLQDKLA QIRDARGALSALREEHREKLRRAAE EAERQRQIQLAQKLEIMRQKKQEYL EVQRQLAIQRLQEQEKERQMRLEQQ KQTVQMRAQMPAFPLPYAQLQAMPA AGGVLYQPSGPASFPSTFSPAGSVE GSPMHGVYMSQPAPAAGPYPSMPST AADPSMVSAYMYPAGATGAQAAPQA QAGPTASPAYSSYQPTPTAGYQNVA SQAPQSLPAISQPPQSSTMGYMGSQ SVSMGYQPYNMQNLMTTLPSQDASL PPQQPYIAGQQPMYQQMAPSGGPPQ QQPPVAQQPQAQGPPAQGSEAQLIS FD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HGS hepatocyte growth factor-regulated tyrosine kinase substrate [ Homo sapiens ]
• Official Symbol: HGS
• Synonyms: HGS; hepatocyte growth factor-regulated tyrosine kinase substrate; Hrs; Vps27; ZFYVE8; protein pp110; human growth factor-regulated tyrosine kinase substrate; HRS; FLJ11421; FLJ39878
• Gene ID: 9146
• mRNA Refseq: NM_004712
• Protein Refseq: NP_004703
• MIM: 604375
• UniProt ID: O14964