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Recombinant Full Length Human IFNA1 Protein, C-Flag-tagged

Cat.No. : IFNA1-1816HFL
Product Overview : Recombinant Full Length Human IFNA1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.
  • Specification
  • Gene Information
  • Related Products
Description : This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia.
Source : Mammalian cells
Species : Human
Tag : Flag
Form : 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 19.3 kDa
AA Sequence : MASPFALLMALVVLSCKSSCSLGCD LPETHSLDNRRTLMLLAQMSRISPS SCLMDRHDFGFPQEEFDGNQ FQKAPAISVLHELIQQIFNLFTTKD SSAAWDEDLLDKFCTELYQQLNDLE ACVMQEERVGETPLMNADSI LAVKKYFRRITLYLTEKKYSPCAWE VVRAEIMRSLSLSTNLQERLRRKE TRTRPLEQKLISEEDLAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 ug/mL as determined by microplate BCA method.
Preparation : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families : Druggable Genome
Protein Pathways : Antigen processing and presentation, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Regulation of autophagy, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Gene Name : IFNA1 interferon alpha 1 [ Homo sapiens (human) ]
Official Symbol : IFNA1
Synonyms : IFL; IFN; IFNA@; IFNA13; leIF D; IFN-ALPHA; IFN-alphaD
Gene ID : 3439
mRNA Refseq : NM_024013.3
Protein Refseq : NP_076918.1
MIM : 147660
UniProt ID : P01562

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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