Recombinant Full Length Human ITGA4 Protein, C-Flag-tagged
Cat.No. : | ITGA4-664HFL |
Product Overview : | Recombinant Full Length Human ITGA4 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 111.2 kDa |
AA Sequence : | MAWEARREPGPRRAAVRETVMLLLC LGVPTGRPYNVDTESALLYQGPHNT LFGYSVVLHSHGANRWLLVG APTANWLANASVINPGAIYRCRIGK NPGQTCEQLQLGSPNGEPCGKTCLE ERDNQWLGVTLSRQPGENGS IVTCGHRWKNIFYIKNENKLPTGGC YGVPPDLRTELSKRIAPCYQDYVKK FGENFASCQAGISSFYTKDL IVMGAPGSSYWTGSLFVYNITTNKY KAFLDKQNQVKFGSYLGYSVGAGHF RSQHTTEVVGGAPQHEQIGK AYIFSIDEKELNILHEMKGKKLGSY FGASVCAVDLNADGFSDLLVGAPMQ STIREEGRVFVYINSGSGAV MNAMETNLVGSDKYAARFGESIVNL GDIDNDGFEDVAIGAPQEDDLQGAI YIYNGRADGISSTFSQRIEG LQISKSLSMFGQSISGQIDADNNGY VDVAVGAFRSDSAVLLRTRPVVIVD ASLSHPESVNRTKFDCVENG WPSVCIDLTLCFSYKGKEVPGYIVL FYNMSLDVNRKAESPPRFYFSSNGT SDVITGSIQVSSREANCRTH QAFMRKDVRDILTPIQIEAAYHLGP HVISKRSTEEFPPLQPILQQKKEKD IMKKTINFARFCAHENCSAD LQVSAKIGFLKPHENKTYLAVGSMK TLMLNVSLFNAGDDAYETTLHVKLP VGLYFIKILELEEKQINCEV TDNSGVVQLDCSIGYIYVDHLSRID ISFLLDVSSLSRAEEDLSITVHATC ENEEEMDNLKHSRVTVAIPL KYEVKLTVHGFVNPTSFVYGSNDEN EPETCMVEKMNLTFHVINTGNSMAP NVSVEIMVPNSFSPQTDKLF NILDVQTTTGECHFENYQRVCALEQ QKSAMQTLKGIVQFLSKTDKRLLYC IKADPHCLNFLCNFGKMESG KEASVHIQLEGRPSILEMDETSALK FEIRATGFPEPNPRVIELNKDENVA HVLLEGLHHQRPKRYFTIVI ISSSLLLGLIVLLLISYVMWKAGFF KRQYKSILQEENRRDSWSYINSKSN DDTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways : | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Regulation of actin cytoskeleton |
Gene Name : | ITGA4 integrin subunit alpha 4 [ Homo sapiens (human) ] |
Official Symbol : | ITGA4 |
Synonyms : | IA4; CD49D |
Gene ID : | 3676 |
mRNA Refseq : | NM_000885.6 |
Protein Refseq : | NP_000876.3 |
MIM : | 192975 |
UniProt ID : | P13612 |
Products Types
◆ Recombinant Protein | ||
ITGA4-2340H | Recombinant Human ITGA4 Protein, His-tagged | +Inquiry |
ITGA4-1210H | Recombinant Human ITGA4 Protein, His (Fc)-Avi-tagged | +Inquiry |
ITGA4-4998H | Recombinant Human ITGA4 Protein | +Inquiry |
Itga4-3595M | Recombinant Mouse Itga4 Protein, Myc/DDK-tagged | +Inquiry |
Itga4-1696M | Recombinant Mouse Itga4 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ITGA4-5133HCL | Recombinant Human ITGA4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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