| Description : |
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Form : |
25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
| Molecular Mass : |
88.4 kDa |
| Protein Length : |
798 amino acids |
| AA Sequence : |
MNLQPIFWIGLISSVCCVFAQTDEN RCLKANAKSCGECIQAGPNCGWCTN STFLQEGMPTSARCDDLEALKKKGC PPDDIENPRGSKDIKKNKNVTNRSK GTAEKLKPEDITQIQPQQLVLRLRS GEPQTFTLKFKRAEDYPIDLYYLMD LSYSMKDDLENVKSLGTDLMNEMRR ITSDFRIGFGSFVEKTVMPYISTTP AKLRNPCTSEQNCTSPFSYKNVLSL TNKGEVFNELVGKQRISGNLDSPEG GFDAIMQVAVCGSLIGWRNVTRLLV FSTDAGFHFAGDGKLGGIVLPNDGQ CHLENNMYTMSHYYDYPSIAHLVQK LSENNIQTIFAVTEEFQPVYKELKN LIPKSAVGTLSANSSNVIQLIIDAY NSLSSEVILENGKLSEGVTISYKSY CKNGVNGTGENGRKCSNISIGDEVQ FEISITSNKCPKKDSDSFKIRPLGF TEEVEVILQYICECECQSEGIPESP KCHEGNGTFECGACRCNEGRVGRHC ECSTDEVNSEDMDAYCRKENSSEIC SNNGECVCGQCVCRKRDNTNEIYSG KFCECDNFNCDRSNGLICGGNGVCK CRVCECNPNYTGSACDCSLDTSTCE ASNGQICNGRGICECGVCKCTDPKF QGQTCEMCQTCLGVCAEHKECVQCR AFNKGEKKDTCTQECSYFNITKVES RDKLPQPVQPDPVSHCKEKDVDDCW FYFTYSVNGNNEVMVHVVENPECPT GPDIIPIVAGVVAGIVLIGLALLLI WKLLMIIHDRREFAKFEKEKMNAKW DTGENPIYKSAVTTVVNPKYEGK |
| Applications : |
Antibody Production; Functional Study: Recommended usage only, not validated yet; Compound Screening: Recommended usage only, not validated yet. |
| Notes : |
Heating may cause protein aggregation. Please do not heat this product before electrophoresis. Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
