Recombinant Full Length Human IVD Protein, GST-tagged

• Cat.No.: IVD-5848HF
• Product Overview: Human IVD full-length ORF ( AAH17202, 1 a.a. - 423 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 72.27 kDa
• Protein Length: 423 amino acids
• AA Sequence: MATATRLLGCRVASWRLRPPLAGFV SQRAHSLLPVDDAINGLSEEQRQLR QTMAKFLQEHLAPKAQEIDRSNEFK NLREFWKQLGNLGVLGITAPVQYGG SGLGYLEHVLVMEEISRASGAVGLS YGAHSNLCINQLVRNGNEAQKEKYL PKLISGEYIGALAMSEPNAGSDVVS MKLKAEKKGNHYILNGNKFWITNGP DADVLIVYAKTDLAAVPASRGITAF IVEKGMPGFSTSKKLDKLGMRGSNT CELIFEDCKIPAANILGHENKGVYV LMSGLDLERLVLAGGPLGLMQAVLD HTIPYLHVREAFGQKIGHFQLMQGK MADMYTRLMACRQYVYNVAKACDEG HCTAKDCAGVILYSAECATQVALDG IQCFGGNGYINDFPMGRFLRDAKLY EIGAGTSEVRRLVIGRAFNADFH
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: IVD isovaleryl-CoA dehydrogenase [ Homo sapiens ]
• Official Symbol: IVD
• Synonyms: IVD; isovaleryl-CoA dehydrogenase; isovaleryl CoA dehydrogenase , isovaleryl Coenzyme A dehydrogenase; isovaleryl-CoA dehydrogenase, mitochondrial; ACAD2; isovaleryl CoA dehydrogenase; isovaleryl Coenzyme A dehydrogenase; FLJ12715; FLJ34849
• Gene ID: 3712
• mRNA Refseq: NM_001159508
• Protein Refseq: NP_001152980
• MIM: 607036
• UniProt ID: P26440