Recombinant Full Length Human KDM1A Protein, C-Flag-tagged

• Cat.No.: KDM1A-747HFL
• Product Overview: Recombinant Full Length Human KDM1A Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 95.6 kDa
• AA Sequence: MLSGKKAAAAAAAAAAAATGTEAGP GTAGGSENGSEVAAQPAGLSGPAEV GPGAVGERTPRKKEPPRASP PGGLAEPPGSAGPQAGPTVVPGSAT PMETGIAETPEGRRTSRRKRAKVEY REMDESLANLSEDEYYSEEE RNAKAEKEKKLPPPPPQAPPEEENE SEPEEPSGQAGGLQDDSSGGYGDGQ ASGVEGAAFQSRLPHDRMTS QEAACFPDIISGPQQTQKVFLFIRN RTLQLWLDNPKIQLTFEATLQQLEA PYNSDTVLVHRVHSYLERHG LINFGIYKRIKPLPTKKTGKVIIIG SGVSGLAAARQLQSFGMDVTLLEAR DRVGGRVATFRKGNYVADLG AMVVTGLGGNPMAVVSKQVNMELAK IKQKCPLYEANGQADTVKVPKEKDE MVEQEFNRLLEATSYLSHQL DFNVLNNKPVSLGQALEVVIQLQEK HVKDEQIEHWKKIVKTQEELKELLN KMVNLKEKIKELHQQYKEAS EVKPPRDITAEFLVKSKHRDLTALC KEYDELAETQGKLEEKLQELEANPP SDVYLSSRDRQILDWHFANL EFANATPLSTLSLKHWDQDDDFEFT GSHLTVRNGYSCVPVALAEGLDIKL NTAVRQVRYTASGCEVIAVN TRSTSQTFIYKCDAVLCTLPLGVLK QQPPAVQFVPPLPEWKTSAVQRMGF GNLNKVVLCFDRVFWDPSVN LFGHVGSTTASRGELFLFWNLYKAP ILLALVAGEAAGIMENISDDVIVGR CLAILKGIFGSSAVPQPKET VVSRWRADPWARGSYSYVAAGSSGN DYDLMAQPITPGPSIPGAPQPIPRL FFAGEHTIRNYPATVHGALL
  SGLREAGRIADQFLGAMYTLPRQAT PGVPAQQSPSMTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transcription Factors

Gene Information

• Gene Name: KDM1A lysine demethylase 1A [ Homo sapiens (human) ]
• Official Symbol: KDM1A
• Synonyms: AOF2; CPRF; KDM1; LSD1; BHC110
• Gene ID: 23028
• mRNA Refseq: NM_001009999.3
• Protein Refseq: NP_001009999.1
• MIM: 609132
• UniProt ID: O60341